Journal ArticleDOI
Reviewing the role of emerging therapies in the ADHD armamentarium.
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TLDR
A robust pipeline of stimulants and nonstimulants in development are found, formulated to optimize onset and duration of effect, alter the time of administration, obviate the need to swallow whole capsules or tablets and to deter abuse.Abstract:
Introduction: Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral disorder that can be treated with both pharmacologic and nonpharmacologic modalities. Effective drug treatm...read more
Citations
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Meta-analysis of organizational skills interventions for children and adolescents with Attention-Deficti/Hyperactivity Disorder
TL;DR: In this article, the authors conducted a systematic review and meta-analysis of OST in children with ADHD and found that OST leads to moderate improvements in organizational skills as rated by teachers and large improvements by parents, while more modest improvements were observed on the ratings of symptoms of inattention and academic performance.
Journal ArticleDOI
Updates in Pharmacologic Strategies in Adult Attention-Deficit/Hyperactivity Disorder.
TL;DR: A review of FDA approved and emerging medication options while providing guidelines for pharmacologic management of adult ADHD is presented in this paper . But, limitations still persist in available psychotropics for certain patient populations such as those with comorbid substance use or cardiovascular illness.
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111 Phase 3, Randomized, Double-Blind, Placebo-Controlled Study (P301) Assessing Efficacy and Safety of Extended-Release Viloxazine in Children with ADHD
TL;DR: In this study, SPN-812 at 100 mg and 200 mg doses met the primary and secondary objectives with statistical significance and was well tolerated in children ages 6-11yrs with ADHD.
References
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Journal ArticleDOI
Misuse of Stimulant Medication Among College Students: A Comprehensive Review and Meta-analysis
TL;DR: The purpose of this review and meta-analysis is to summarize the current research on rates and demographic and psychosocial correlates of stimulant medication misuse among college students, to provide methodological guidance and other ideas for future research, and to provide some preliminary suggestions for preventing and reducing misuse on college campuses.
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Treatment of Attention-Deficit/Hyperactivity Disorder in Adolescents: A Systematic Review
TL;DR: Evidence supports the use of extended- release methylphenidate and amphetamine formulations, atomoxetine, and extended-release guanfacine to improve symptoms of ADHD in adolescents and greater benefit for academic and organizational skills.
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Illicit methylphenidate use in an undergraduate student sample: prevalence and risk factors.
TL;DR: To assess the prevalence of illicit methylphenidate use among undergraduate college students at a large university, and to identify alcohol and other drug use behaviors, as well as the negative consequences and risk factors, associated with illicit methyl phenidate use.
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Guanfacine extended release in children and adolescents with attention-deficit/hyperactivity disorder: a placebo-controlled trial.
TL;DR: Guanfacine extended-release was effective in reducing symptoms of ADHD, and adverse events were mild to moderate, did not interfere with improvements in attention, and rarely led to discontinuation.
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The neuropharmacology of ADHD drugs in vivo: insights on efficacy and safety.
TL;DR: The development of once-daily psychostimulant formulations and a prodrug, lisdexamfetamine, has improved patient compliance and markedly reduced scope for their diversion/abuse.