Journal ArticleDOI
Ring‐Selective Synthesis of O‐Heterocycles from Acyclic 3‐O‐Allyl‐monosaccharides via Intramolecular Nitrone—Alkene Cycloaddition.
Tony K. M. Shing,Yong-Li Zhong +1 more
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TLDR
In this article, 1,3-dipolar cycloadditions of nitrones formed from 3-O-allyl- d -glucose and d -altrose (both with threo-configuration at C-2,3) afford oxepanes selectively whereas the same reactions of the same nitrones derived from 3 O-alll-d -allose and D -mannose, both with erythroconfiguration, give tetrahydropyrans selectively.Abstract:
Intramolecular 1,3-dipolar cycloadditions of nitrones formed from 3-O-allyl- d -glucose and d -altrose (both with threo-configuration at C-2,3) afford oxepanes selectively whereas the same reactions of nitrones derived from 3-O-allyl- d -allose and d -mannose (both with erythro-configuration at C-2,3) give tetrahydropyrans selectively.read more
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Synthesis of O-1-O-6 Substituted Positional Isomers of D-Glucose-Thioether Ligands and Their Ruthenium Polypyridyl Conjugates
TL;DR: A protecting group strategy without the necessity of using palladium on carbon for the modification for the 2-O and 4-O position allows for the incorporation of sulfur donor atoms as ligands for transition metal complexes.
Journal ArticleDOI
Synthesis, Characterization and Antibacterial Activity of Macrocyclic Schiff Bases Based on 1,3-Docarbonyl Phenyl Dihydrazide, 1,4-Docarbonyl Phenyl Dihydrazide
TL;DR: In this paper, three new Macrocyclic Hydrazone Schiff bases were synthesized by condensation of intermediate compounds: 1,6- bis hexane and glutaraldehyde with both dihydrazide of isophthalic acid and dihydraide of terephthalic acid.
Journal ArticleDOI
Synthesis of (3R,4S)-3,4,5-Trihydroxy-4-methylpentylphosphonic Acid as a Potential Inhibitor of the Nonmevalonate Pathway
TL;DR: The synthesis of (3R,4S)-3,4,5-trihydroxy-4-methylpentylphosphonic acid is described as a candidate for inhibiting MEP cytidylyltransferase, which is the third step on the nonmevalonate pathway.
References
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Journal ArticleDOI
Ring-selective synthesis of O-heterocycles from acyclic 3-O-allyl-monosaccharides via intramolecular nitrone–alkene cycloaddition
Tony K. M. Shing,Yong-Li Zhong +1 more
TL;DR: In this article, 1,3-dipolar cycloadditions of nitrones formed from 3-O-allyl- d -glucose and d -altrose (both with threo-configuration at C-2,3) afford oxepanes selectively whereas the same reactions of the same nitrones derived from 3 O-alll-d -allose and D -mannose, both with erythroconfiguration, give tetrahydropyrans selectively.
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