Journal ArticleDOI
Risk assessment of ciprofloxacin, flavomycin, olaquindox and colistin sulfate based on microbiological impact on human gut biota
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TLDR
The colonization barrier disruption effect of ciprofloxacin, flavomycin, olaquindox and colistin sulfate is investigated by the minimum inhibitory concentration (MIC) assay in pure culture of human gut bacteria and the no-observed-effect-concentration (NOEC) and acceptable daily intake (ADI) based on the microbiological impact are evaluated.About:
This article is published in Regulatory Toxicology and Pharmacology.The article was published on 2009-04-01. It has received 52 citations till now. The article focuses on the topics: Colistin.read more
Citations
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'Gut health': a new objective in medicine?
TL;DR: The GI barrier adjacent to the GI microbiota appears to be the key to understanding the complex mechanisms that maintain gut health and methods of assessing, improving and maintaining gut health-related GI functions are of major interest in preventive medicine.
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Antibiotic use and microbiome function.
TL;DR: A critical review of the antibiotics or antibiotic cocktails whose use in humans has been linked to changes in the composition of the authors' microbial communities, with a particular focus on the gut, oral, respiratory, skin and vaginal microbiota, and on their molecular agents (genes, proteins and metabolites).
Journal ArticleDOI
The gut is the epicentre of antibiotic resistance
TL;DR: After the destruction of resistant colonizing bacteria, which has been successfully obtained in several studies, the gut could be re-colonized with normal faecal flora or probiotic, and studies are warranted to evaluate this concept.
Journal ArticleDOI
Enhanced nitrogen removal from pharmaceutical wastewater using SBA-ANAMMOX process
Chong-Jian Tang,Ping Zheng,Tingting Chen,Jiqiang Zhang,Qaisar Mahmood,Shuang Ding,Xiao-Guang Chen,Jianwei Chen,Da-Tian Wu +8 more
TL;DR: The application of SBA-ANAMMOX process in refractory ammonium-rich wastewater is promising, and the biotoxicity assay on luminescent bacterium Photobacterium phosphoreum showed that the pharmaceutical wastewater imparted severe toxicity.
Journal ArticleDOI
Bright Yellow Fluorescent Carbon Dots as a Multifunctional Sensing Platform for the Label-Free Detection of Fluoroquinolones and Histidine.
Lu Wenjing,Lu Wenjing,Yuan Jiao,Yifang Gao,Jie Qiao,Jie Qiao,Maedeh Mozneb,Shaomin Shuang,Chuan Dong,Chen-Zhong Li +9 more
TL;DR: The Y-CDs with superior optical and biological merits including high chemical stability, good biocompatibility, and low cytotoxicity were successfully employed for trace detection of FQs in real samples such as antibiotic tablets and milk products and prove that this multifunctional sensing platform presents great prospect in multiple applications such as biosensing, biomedicine, disease diagnosis, and environmental monitoring.
References
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Journal ArticleDOI
National Committee for Clinical Laboratory Standards.
TL;DR: Many members of the Academy of Pediatrics seem to be generally unaware of the fact that the Academy has participated for ten years in a very interesting and valuable organization, the National Committee for Clinical Laboratory Standards (NCCLS).
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Probiotics in man and animals
TL;DR: In this paper, the authors used probiotic treatments to re-establish the natural condition which exists in the wild animal but which has been disrupted by modern trends in conditions used for rearing young animals, including human babies, and in modern approaches to nutrition and disease therapy.
Journal Article
Probiotics in man and animals
TL;DR: These are all areas where the gut flora can be altered for the worse and where, by the administration of probiotics, the natural balance of the gut microflora can be restored and the animal returned to its normal nutrition, growth and health status.
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Colistin: The Revival of Polymyxins for the Management of Multidrug-Resistant Gram-Negative Bacterial Infections
TL;DR: Recent studies of patients who received intravenous polymyxins for the treatment of serious P. aeruginosa and Acinetobacter baumannii infections of various types, including pneumonia, bacteremia, and urinary tract infections, have led to the conclusion that these antibiotics have acceptable effectiveness and considerably less toxicity than was reported in old studies.
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Human fecal flora: the normal flora of 20 Japanese-Hawaiians.
TL;DR: Quantitative and qualitative examination of the fecal flora of 20 clinically healthy Japanese-Hawaiian males was carried out by using anaerobic tube culture techniques, and differential characteristics of previously unreported species are presented.