scispace - formally typeset
Journal ArticleDOI

Роль изменений экспрессии Homer1 в чувствительности к стрессу

В.В. Решетников, +1 more
- Vol. 86, Iss: 6, pp 755-770
About
The article was published on 2021-06-01. It has received 2 citations till now.

read more

Citations
More filters

Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors

TL;DR: It is demonstrated that the adaptor protein, termed Homer, facilitates a physical association between TRPC1 and the IP(3)R that is required for the TRP channel to respond to signals.
Journal Article

Epigenetic modulation of homer1a transcription regulation in amygdala and hippocampus with Pavlovian fear conditioning

TL;DR: In this article, the authors examined whether Homer1a is necessary for Pavlovian cued fear conditioning, whether it is downstream of BDNF-TrkB activation, and whether this pathway utilizes histone modifications for activity-dependent transcriptional regulation.
References
More filters
Journal ArticleDOI

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

TL;DR: It is proposed that the AU sequences are the recognition signal for an mRNA processing pathway which specifically degrades the mRNAs for certain lymphokines, cytokines, and proto-oncogenes.
Journal ArticleDOI

Homeostatic plasticity in the developing nervous system

TL;DR: Evidence is discussed from a number of systems that homeostatic synaptic plasticity is crucial for processes ranging from memory storage to activity-dependent development, and how these processes maintain stable activity states in the face of destabilizing forces is discussed.
Journal ArticleDOI

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

TL;DR: The widespread expression of mGluRs makes these receptors particularly attractive drug targets, and recent studies continue to validate the therapeutic utility of m GluR ligands in neurological and psychiatric disorders such as Alzheimer's disease, Parkinson's Disease, anxiety, depression, and schizophrenia.
Journal ArticleDOI

The neuro-symphony of stress

TL;DR: Together, the effects of individual mediators on neuronal function and plasticity are integrated, and emerging evidence suggests that there is crosstalk between them that enables fine-tuned responses to diverse challenges.
Journal ArticleDOI

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

TL;DR: Understanding of the mechanisms by which stress and glucocorticoids affect glutamate transmission provides insights into normal brain functioning, as well as the pathophysiology and potential new treatments of stress-related neuropsychiatric disorders.