Journal ArticleDOI
Role of In Vivo Proton Magnetic Resonance Spectroscopy in the Diagnosis and Management of Brain Abscesses
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TLDR
In vivo proton magnetic resonance spectroscopy was performed for 24 patients with pyogenic brain abscesses to examine the consistency of the spectral patterns and to observe the changes in metabolites with treatment, and it was concluded that spectral patterns for brainAbscesses are consistent and specific and can assist in the noninvasive diagnosis of abscesss.Abstract:
OBJECTIVE: In vivo proton magnetic resonance spectroscopy was performed for 24 patients with pyogenic brain abscesses, to examine the consistency of the spectral patterns and to observe the changes in metabolites with treatment. METHODS: Localized proton spectra were obtained from 4- to 8-ml volumes in the abscesses, using stimulated echo acquisition mode and spin echo sequences. Twenty-two patients were treated with combined surgical and medical therapy, and two patients were treated conservatively. High-resolution magnetic resonance spectroscopy was performed for 15 samples of abscesses obtained from these patients, to confirm the assignments of resonances seen in vivo. Postaspiration studies were performed for 12 patients treated with combined medical and surgical therapy and 2 patients treated medically. RESULTS: Lactate and amino acids were seen in spectra for all patients, irrespective of the time of spectroscopy after the onset of combined medical and surgical therapy. Acetate and pyruvate disappeared after 1 week of combined treatment. CONCLUSION: It was concluded that spectral patterns for brain abscesses are consistent and specific and can assist in the noninvasive diagnosis of abscesses. Responses to combined treatment could be monitored by showing the changes in metabolite patterns in serial spectroscopic studies.read more
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Brain abscess and necrotic brain tumor: discrimination with proton MR spectroscopy and diffusion-weighted imaging.
TL;DR: Proton MR spectroscopy and diffusion-weighted imaging are useful for differentiating brain abscess from brain tumor, but the latter requires less time and is more accurate than is (1)H-MRS.
Journal ArticleDOI
Unusual lesions of the cerebellopontine angle: a segmental approach.
Fabrice Bonneville,Jean-Luc Sarrazin,Kathlyn Marsot-Dupuch,Clément Iffenecker,Yves-Sébastien Cordoliani,Dominique Doyon,Jean-François Bonneville +6 more
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Differentiation of tuberculous from pyogenic brain abscesses with in vivo proton MR spectroscopy and magnetization transfer MR imaging.
Rakesh K. Gupta,Davender K. Vatsal,Nuzat Husain,Sanjeev Chawla,Kashi N. Prasad,Raja Roy,Rajesh Kumar,Deepak Kumar Jha,Mazhar Husain +8 more
TL;DR: It might be possible to differentiate tuberculous abscesses from pyogenic abscesss by using MT MR imaging and in vivo MR spectroscopy, which could be of value in influencing the management of such cases.
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Brain abscesses: etiologic categorization with in vivo proton MR spectroscopy.
Monika Garg,Rakesh K. Gupta,Mazhar Husain,Sanjeev Chawla,Jayant Chawla,Rajesh Kumar,Sajja B. Rao,Mithlesh K. Misra,Kashi N. Prasad +8 more
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Imaging of cerebellopontine angle lesions: an update. Part 2: intra-axial lesions, skull base lesions that may invade the CPA region, and non-enhancing extra-axial lesions.
TL;DR: The pertinent neuroimaging features that radiologists need to know to make clinically relevant diagnoses in these cases are explained, including data from diffusion- and perfusion-weighted imaging or MR spectroscopy, when available.
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Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
TL;DR: In vivo proton MR spectroscopy, helps in tissue characterization of intracranial mass lesions and is a reliable technique for grading of gliomas when N-acetyl-aspartate/choline and choline/creatine ratios and presence of lipids are used in combination.
Journal ArticleDOI
Improved management of multiple brain abscesses: a combined surgical and medical approach.
TL;DR: A combined surgical and medical approach should yield cure rates of more than 90% in patients with multiple brain abscesses, a result similar to that expected when treating patients with solitary lesions.