Journal ArticleDOI
Roles of alpha1- and beta-adrenergic receptors in adrenergic responsiveness of liver cells formed after partial hepatectomy
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TLDR
It appears that during the process of liver regeneration which follows partial hepatectomy there is a transition in the type of adrenergic receptor involved in the hepatic actions of catecholamines from β in the initial stages to later α 1, a similar transition seems to occur as the animal ages.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1983-09-22. It has received 51 citations till now. The article focuses on the topics: Adrenergic receptor & Beta-3 adrenergic receptor.read more
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Journal ArticleDOI
Stimulatory and inhibitory effects of catecholamines on DNA synthesis in primary rat hepatocyte cultures : role of alpha1-and beta-adrenergic mechanisms
TL;DR: Catecholamines, via β‐adrenoceptors and cyclic AMP, inhibit the G1‐S transition, and may thus play a role in the termination of hepatic proliferation.
Book ChapterDOI
The roles of calcium and phosphoinositides in the mechanisms of alpha 1-adrenergic and other agonists.
Journal ArticleDOI
Dual effects of glucagon and cyclic AMP on DNA synthesis in cultured rat hepatocytes: stimulatory regulation in early G1 and inhibition shortly before the S phase entry.
G. Hege Thoresen,Tor-Erik Sand,Magne Refsnes,Olav Dajani,Tormod Kyrre Guren,Ivar P. Gladhaug,Anne Killi,Thoralf Christoffersen +7 more
TL;DR: The results indicate that cyclic AMP has dual effects on hepatocyte proliferation with a stimulatory modulation early in the prereplicative period (Go or early G1), and a marked inhibition exerted immediately before the transition from G1 to S phase.
Journal ArticleDOI
Regulation of hepatocyte growth: alpha-1 adrenergic receptor and ras p21 changes in liver regeneration.
TL;DR: A role for alpha‐1 receptors and ras protein in the early events of liver regeneration is suggested, with a significant loss of specific [3H]‐prazosin binding to cells isolated from rat livers 48 and 72 hr after PHX.
Journal ArticleDOI
Beta adrenergic regulation of rat liver glycogenolysis during aging
TL;DR: It is proposed that current concepts of alpha adrenergic-responsive liver glycogenolysis underestimate a physiological role for beta adrenergic responsiveness over the majority of the life span.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Phosphorus Assay in Column Chromatography
TL;DR: If the highest accuracy was not required, the following manipulations simplified and speeded multiple total phosphorus determinations on the eluates from column chromatographic separations.
Journal ArticleDOI
HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS: A Biochemical and Fine Structural Study
M. N. Berry,Daniel S. Friend +1 more
TL;DR: Cytoplasmic vacuolization in a small percentage of cells and potassium loss are the only indications of cell injury detected, and the isolated cells are comparable to normal hepatic parenchymal cells in situ in appearance and function.