Open AccessJournal Article
Sensitive and simple method for the determination of nicotine and cotinine in human urine, plasma and saliva by gas chromatography-mass spectrometry
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In this paper, a method was proposed for the determination of nicotine and cotinine in human urine, plasma and saliva, and the results showed that through the accurate determination of cotinines in saliva, the risk of ETS-exposed human can be predicted.About:
This article is published in Journal of Chromatography B: Biomedical Sciences and Applications.The article was published on 2002-01-01 and is currently open access. It has received 104 citations till now. The article focuses on the topics: Cotinine & Nicotine.read more
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Journal ArticleDOI
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: In those older than age 50, systolic blood pressure of greater than 140 mm Hg is a more important cardiovascular disease (CVD) risk factor than diastolic BP, and hypertension will be controlled only if patients are motivated to stay on their treatment plan.
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Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry
TL;DR: The method enables quantification of endogenous plasma concentrations of 16 analytes related to B-vitamin status and inflammation, and may prove useful in large-scale epidemiological studies.
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Biomarkers of oxidative damage in cigarette smokers: which biomarkers might reflect acute versus chronic oxidative stress?
Raymond C.S. Seet,Chung-Yung J. Lee,Wai Mun Loke,Shan Hong Huang,Huiwen Huang,Woan Foon Looi,Eng Soh Chew,Amy M.L. Quek,Erle C.H. Lim,Barry Halliwell +9 more
TL;DR: It is confirmed that certain oxidative damage biomarkers are elevated in smokers even after a period of abstinence from smoking, whereas these plus some others are elevated after acute smoking.
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Bioanalytical procedures for monitoring in utero drug exposure.
TL;DR: Bioanalytical methods for in utero drug exposure monitoring for common drugs of abuse in urine, hair, oral fluid, blood, sweat, meconium, amniotic fluid, umbilical cord tissue, nails, and vernix caseosa are reviewed; neonatal matrices are particularly emphasized.
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Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods.
TL;DR: Methods to assess tobacco smoke exposure and biomarkers used for determining the smoking status of an individual are compared and cortisol, a stress hormone speculated to be linked to nicotine metabolism, is discussed.
References
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Daniel W. Jones,Barry J. Materson +6 more
TL;DR: Aram V. Chobanian, MDGeorge L. Bakris, MDHenry R. Black, MDWilliam C. Cushman, MDLee A. Green, MD, MPHJoseph L. Izzo, Jr, MDDaniel W. Jones, MDBarry J. Materson, MBASuzanne Oparil, MDJackson T. Wright, Jr., MD, PhDEdward J. Roccella, PhD, MPHand the National High BloodPressure Education ProgramCoordinating Committee
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Cotinine as a Biomarker of Environmental Tobacco Smoke Exposure
TL;DR: A biomarker is desirable in quantitating systemic exposure both in smokers and nonsmokers to constituents of tobacco smoke to reflect exposure to toxic constituents of smoke that are of concern.
The health consequences of involuntary smoking : a report of the Surgeon General
TL;DR: What do you do to start reading health consequences of involuntary smoking a report of the surgeon general?
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Environmental tobacco smoke. Measuring exposures and assessing health effects
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Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids
TL;DR: Improved methods have been developed for the determination of nicotine and its major metabolite, cotinine, in blood, plasma, and urine samples by utilizing gas chromatography with alkali flame ionization (nitrogen--phosphorus) detection and structural analogs of Nicotine and cotinines as internal standards.