Journal ArticleDOI
Separation and identification of geometric isomers of retinoic acid and methyl retinoate
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TLDR
Geometric isomers of retinoic acid and methyl retinoate were separated by high-performace liquid chromatography on bonded, reversed-phase, octadecylsilane columns using methanol-water mixtures as solvents as discussed by the authors.About:
This article is published in Journal of Chromatography A.The article was published on 1978-08-11. It has received 35 citations till now. The article focuses on the topics: Cis–trans isomerism.read more
Citations
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Journal ArticleDOI
The function of vitamin A: current concepts.
Maija H. Zile,Malford E. Cullum +1 more
TL;DR: Visual function of vitamin A: a. growth, b. Membrane phenomena.
Journal ArticleDOI
Identification of 5,6-epoxyretinoic acid as an endogenous retinol metabolite.
A M McCormick,J L Napoli +1 more
TL;DR: Retinoic Acid and its metabolite 5,6-epoxyretinoic acid are endogenous rat kidney retinoids which are in the pathway of retinol metabolism under physiological conditions and are comparatively significant vitamin A metabolites in kidney.
Journal ArticleDOI
Investigation on the photostability of a tretinoin lotion and stabilization with additives.
TL;DR: The addition of the yellow colourants chrysoin and fast yellow did indeed retard the photo-degradation of tretinoin more or less depending on the concentration of the dye and Irradiation with selected wavelengths revealed that 420 nm seemed to be the most harmful wavelength for the degradation of t retinoin.
Journal ArticleDOI
Gas chromatographic—mass spectrometric assay for low levels of retinoic acid in human blood
TL;DR: A rapid and sensitive method of analysis for retinoic acid in human blood has been developed using gas chromatography-mass spectrometry for separation and detection.
Journal ArticleDOI
Separation and identification of retinoic acid photo-isomers
M.G. Motto,K.L. Facchine,P.F. Hamburg,David J. Burinsky,Richard Dunphy,Alan R. Oyler,Mary Lou Cotter +6 more
TL;DR: In this article, the retinoic acid was isomerized in ethanol water (90:10) with fluorescent light and the variation of product distribution with time was determined over the course of the reaction.
References
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Journal ArticleDOI
Esterification of Fatty Acids with Diazomethane on a Small Scale
H. Schlenk,Joanne L. Gellerman +1 more
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Chemistry of Vitamin A. XXV. Geometrical Isomers of Vitamin A Aldehyde and an Isomer of its α-Ionone Analog1
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Physical organic methods in carotenoid research
TL;DR: The ever increasing importance of physical methods in the elucidation of the structure and configuration of carotenoids is reviewed and mass spectroscopic studies of the characteristic fragmentation of the carotenes, and a possible mechanism for the fragmentation ofThe polyene chain, are discussed in detail.
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Applications of high-pressure liquid chromatography and gas chromatography to problems in vitamin A analysis.
TL;DR: It was demonstrated that high-pressure liquid chromatography surpasses gas chromatography as an analytical tool for this application and is shown to be an effective tool for vitamin A analysis.
Journal ArticleDOI
Mass spectra of retinol and related compounds.
TL;DR: The mass spectra of the all-trans-isomers of retinol (vitamin A), anhydroretinol, retinyl acetate, retinal, retinoic acid and methyl retinoate, and 9-cis-retinal were investigated, providing a quick and unambiguous method of identification.