Journal ArticleDOI
Somatostatin-derived amyloid deposition associated with duodenal neuroendocrine tumour (NET): a report of novel localised amyloidosis associated with NET.
Shojiro Ichimata,Shojiro Ichimata,Nagaaki Katoh,Ryuta Abe,Tsuneaki Yoshinaga,Fuyuki Kametani,Masahide Yazaki,Yukiko Kusama,Kenji Sano,Takeshi Uehara,Yoshiki Sekijima +10 more
TLDR
In this paper, the authors reported glucagon-derived localised amyloidosis associated with pancreatic neuroendocrine tumors (NETs) and reported another novicious case.Abstract:
Neuroendocrine tumours (NET) sometimes exhibit amyloid deposition [1]. Previously, we reported glucagon-derived localised amyloidosis associated with pancreatic NET [2]. Here, we report another nov...read more
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Amyloid nomenclature 2022: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee
Joel N. Buxbaum,Angela Dispenzieri,David Eisenberg,Marcus Fändrich,Giampaolo Merlini,M. J. M. Saraiva,Yoshiki Sekijima,Per Westermark +7 more
TL;DR: The nomenclature principles remain unchanged but there is an ongoing discussion regarding the importance and varying nature of intracellular protein aggregates, particularly those associated with neurodegenerative diseases as mentioned in this paper .
References
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Journal ArticleDOI
Functional Amyloids as Natural Storage of Peptide Hormones in Pituitary Secretory Granules
Samir K. Maji,Marilyn H. Perrin,Michael R. Sawaya,Sebastian Jessberger,Krishna C. Vadodaria,Robert A. Rissman,Praful S. Singru,K. Peter R. Nilsson,Rozalyn Simon,David Schubert,David Eisenberg,Jean Rivier,Paul E. Sawchenko,Wylie Vale,Roland Riek,Roland Riek +15 more
TL;DR: It is found that peptide and protein hormones in secretory granules of the endocrine system are stored in an amyloid-like cross–β-sheet–rich conformation, which means functional amyloids in the pituitary and other organs can contribute to normal cell and tissue physiology.
Journal ArticleDOI
Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee.
Merrill D. Benson,Joel N. Buxbaum,David Eisenberg,Giampaolo Merlini,Maria João Saraiva,Yoshiki Sekijima,Jean D. Sipe,Per Westermark +7 more
TL;DR: The ISA Nomenclature Committee met electronically before and directly after the XVII ISA International Symposium on Amyloidosis, which, unfortunately, had to be virtual in September 2020 due to the ongoing COVID-19 pandemic instead of a planned meeting in Tarragona in March.
Journal ArticleDOI
Spontaneous fibrillation of the native neuropeptide hormone Somatostatin-14.
Wilmar van Grondelle,Carmen López Iglesias,Elisenda Coll,Franck Artzner,Maïté Paternostre,Frédéric Lacombe,Merce Cardus,Gema Martínez,Martin Montes,Roland Cherif-Cheikh,Céline Valéry +10 more
TL;DR: It is shown that natural Somatostatin-14 spontaneously self-assembles in water and in 150 mM NaCl into liquid crystalline nanofibrils, which follow characteristic structural features of amyloid fibrils.
Journal ArticleDOI
Ampullary carcinoid with amyloid stroma
TL;DR: 1. An immunohistochemical comparison of chordoma with renal cell carcinoma, colorectal adenocarcinoma, and myxopapillary ependymoma: a potential diagnostic dilemma in the diminutive biopsy.
Journal ArticleDOI
A case of novel amyloidosis: glucagon-derived amyloid deposition associated with pancreatic neuroendocrine tumour.
Shojiro Ichimata,Shojiro Ichimata,Nagaaki Katoh,Ryuta Abe,Tsuneaki Yoshinaga,Fuyuki Kametani,Masahide Yazaki,Takeshi Uehara,Yoshiki Sekijima +8 more
TL;DR: A case of localised amyloid deposition in association with neuroendocrine tumours, such as medullary thyroid carcinoma and pituitary prolactinoma is reported.