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Spectra of data sampled at frequency-modulated rates in application to cardiovascular signals: Part 2. Evaluation of Fourier transform algorithms.

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TLDR
Dividing the effect of PFM in a ‘harmonic’ and ‘aliasing’ distortion, it is found that the FFT has a relatively high harmonic distortion, compared to an algorithm that takes into account the non-uniform character of the data.
Abstract
For three direct Fourier transform algorithms we quantified the influence of pulse frequency modulation (PFM) on the spectral estimation of pulse amplitude modulation (PAM). The simulation study is based on sinusoid functions sampled according to a pulse sequence which is the output of an integral pulse frequency modulator (IPFM). One algorithm exactly reproduces the theoretical spectrum derived in Part 1. The other two, including the classical FFT, scale all PFM-induced components in a different way, and in addition, generate higher modulating frequency harmonics. For a PFM depth below 30%, the sum of spurious PFM components is almost linearly dependent on this modulation depth, for all three algorithms. Dividing the effect of PFM in a ‘harmonic’ and ‘aliasing’ distortion, we found that the FFT has a relatively high harmonic distortion, compared to an algorithm that takes into account the non-uniform character of the data. In the cardiovascular (worst) case of 30% modulation in heart rate (PFM) at a frequency of 0.1 Hz, the FFT spectrum of beat-to-beat systolic blood pressure variations contains approximately 20% of spurious components caused solely by the modulation in time occurrences of the blood pressure samples. The ‘non-uniform’ algorithm performs twice as well in this case.

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Citations
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Sampling frequency of the RR interval time series for spectral analysis of heart rate variability.

TL;DR: This paper shall analyse the RR interval time series from selected subjects for different sampling frequencies to compare the error introduced in selected frequency-domain measures of HRV at a constant frequency resolution for a specific duration of electrocardiogram (ECG) data.
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Subtle involvement of the sympathetic nervous system in amyotrophic lateral sclerosis

TL;DR: The results indicate that the sympathetic nervous system shows subtle abnormalities in ALS, predominantly sympathetic overactivity, and points to the involvement of the preganglionic sympathetic column as the cause of the higher sympathetic activity and the absence of SSR.
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The importance of high-frequency paced breathing in spectral baroreflex sensitivity assessment.

TL;DR: The results demonstrate that the risk of an overestimated BRS value is realistic as long as respiration is not controlled and of high-frequency, and controlled 6/min breathing caused significant BRS overestimation under resting conditions.
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Effects of isoflurane on cardiovascular system and sympathovagal balance in New Zealand white rabbits.

TL;DR: Results indicate that cardiovascular effects induced by isoflurane in smaller animals such as rabbits are similar to those observed in humans and other animal species.
Journal ArticleDOI

Effects of RR segment duration on HRV spectrum estimation.

TL;DR: A comparative analysis for RR interval segment durations has been made and it was concluded that segment length of 256 samples with 50% overlapping provides a smoothed spectral estimate with clearly outlined peaks in low- and high-frequency bands.
References
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Journal ArticleDOI

Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.

TL;DR: The spontaneous beat-to-beat oscillation in R-R interval during control recumbent position, 90° upright tilt, controlled respiration and acute and chronic β-adrenergic receptor blockade was analyzed, indicating that sympathetic nerves to the heart are instrumental in the genesis of low-frequency oscillations in R -R interval.
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Spectrum analysis—A modern perspective

TL;DR: In this paper, a summary of many of the new techniques developed in the last two decades for spectrum analysis of discrete time series is presented, including classical periodogram, classical Blackman-Tukey, autoregressive (maximum entropy), moving average, autotegressive-moving average, maximum likelihood, Prony, and Pisarenko methods.
Journal Article

Assessment of autonomic function in human by heart rate spectral analysis

TL;DR: In this paper, the authors assessed spontaneous heart rate fluctuations by use of autonomic blocking agents and changes in posture, and found that low-frequency fluctuations (below 0.12 Hz) in the supine position are mediated entirely by the parasympathetic nervous system.
Journal ArticleDOI

Assessment of autonomic function in humans by heart rate spectral analysis

TL;DR: In this paper, the authors assessed spontaneous heart rate fluctuations by use of autonomic blocking agents and changes in posture, and found that low-frequency fluctuations (below 0.12 Hz) in the supine position are mediated entirely by the parasympathetic nervous system.
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