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Assessment of autonomic function in humans by heart rate spectral analysis

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TLDR
In this paper, the authors assessed spontaneous heart rate fluctuations by use of autonomic blocking agents and changes in posture, and found that low-frequency fluctuations (below 0.12 Hz) in the supine position are mediated entirely by the parasympathetic nervous system.
Abstract
Spectral analysis of spontaneous heart rate fluctuations were assessed by use of autonomic blocking agents and changes in posture. Low-frequency fluctuations (below 0.12 Hz) in the supine position are mediated entirely by the parasympathetic nervous system. On standing, the low-frequency fluctuations increase and are jointly mediated by the sympathetic and parasympathetic nervous systems. High-frequency fluctuations, at the respiratory frequency, are decreased by standing and are mediated solely by the parasympathetic system. Heart rate spectral analysis is a powerful noninvasive tool for quantifying autonomic nervous system activity.

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Journal ArticleDOI

Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.

TL;DR: The spontaneous beat-to-beat oscillation in R-R interval during control recumbent position, 90° upright tilt, controlled respiration and acute and chronic β-adrenergic receptor blockade was analyzed, indicating that sympathetic nerves to the heart are instrumental in the genesis of low-frequency oscillations in R -R interval.
Journal ArticleDOI

Heart rate variability: Origins, methods, and interpretive caveats

TL;DR: In this article, the authors examined the physiological origins and mechanisms of heart rate variability, considered quantitative approaches to measurement, and highlighted important caveats in the interpretation of heart rates variability, and outlined guidelines for research in this area.
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Heart rate variability: a review

TL;DR: The various applications of HRV and different linear, frequency domain, wavelet domain, nonlinear techniques used for the analysis of the HRV are discussed.
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Diabetic Autonomic Neuropathy

TL;DR: There are studies in progress that suggest that autonomic nerves can be induced to regenerate, and the future for patients with diabetic autonomic neuropathy is brighter.
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Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study.

TL;DR: The estimation of HRV by ambulatory monitoring offers prognostic information beyond that provided by the evaluation of traditional cardiovascular disease risk factors, as well as other relevant risk factors.
References
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Journal ArticleDOI

Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control

TL;DR: It is shown that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz.
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Analysis of heart rate variability.

TL;DR: Results suggest that mean heart rate and variance are unreliable measures, but that consistent changes in interval spectrum occur; these have been traced to alterations mainly in the 0·1 Hz region, perhaps originating with changes in the patterns of respiration which interact with the 0 1 Hz vasomotor activity.
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Postural effects on muscle nerve sympathetic activity in man

TL;DR: P Pulse‐synchronous bursts of multi‐unit sympathetic activity (MSA) were recorded in peroneal muscle nerve fascicles in eight healthy subjects when lying, sitting and standing to study postural changes.
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Modulation of carotid baroreflex responsiveness in man: effects of posture and propranolol

TL;DR: The results suggest that standing enhances baroreflex sensitivity, but that under normal circumstances, this effect is masked by beta-adrenergic stimulation.
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An analysis of the nonlinear behaviour of the human thermal vasomotor control system.

TL;DR: Specific aspects of the activity of the human thermoregulatory system are analysed from the point of view of the associated biological rhythms to show consistency with a nonlinear model of the control system.
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