Journal ArticleDOI
Stereochemical course of glycerol kinase, pyruvate kinase, and hexokinase: phosphoryl transfer from chiral [.gamma.(S)-16O,17O,18O]ATP
About:
This article is published in Journal of the American Chemical Society.The article was published on 1979-01-01. It has received 35 citations till now. The article focuses on the topics: Pyruvate kinase & Pyruvate dehydrogenase kinase.read more
Citations
More filters
Journal ArticleDOI
Investigations of substrate specificity and reaction mechanism of several kinases using chromium(III) adenosine 5'-triphosphate and chromium(III) adenosine 5'-diphosphate.
Journal ArticleDOI
Stereochemical course of phosphokinases. The use of adenosine [gamma-(S)-16O,17O,18O]triphosphate and the mechanistic consequences for the reactions catalyzed by glycerol kinase, hexokinase, pyruvate kinase, and acetate kinase.
TL;DR: It is shown that glycerol kinase and acetate kinase proceed by pathways that result in inversion of the configuration at phosphorus, which provides an access to the otherwise cryptic events that are involved in phosphoryl-group transfer within the ternary complexes of these kinases and their substrates.
Journal ArticleDOI
Stereochemical courses of nucleotidyltransferase and phosphotransferase action. Uridine diphosphate glucose pyrophosphorylase, galactose-1-phosphate uridylyltransferase, adenylate kinase, and nucleoside diphosphate kinase.
Journal ArticleDOI
Stereochemistry of hydrolysis of adenosine 3':5'-cyclic phosphorothioate by the cyclic phosphodiesterase from beef heart.
TL;DR: Adenosine 3':5'-cyclic phosphorothioate, Sp-diastereomer was hydrolyzed by cyclic phosphodiesterase from beef heart in the presence of [18O]water to [ 18O]adenosine 5'-phosphorothIOate, and the result indicates that the hydrolysis proceeded with inversion of configuration at phosphorus.
Related Papers (5)
Synthesis and properties of diastereoisomers of adenosine 5'-(O-1-thiotriphosphate) and adenosine 5'-(O-2-thiotriphosphate).
Fritz Eckstein,Roger S. Goody +1 more
Enzymatic and 32P nuclear magnetic resonance study of adenylate kinase-catalyzed stereospecific phosphorylation of adenosine 5'-phosphorothioate.
K.-F. Rex Sheu,Perry A. Frey +1 more
Stereochemistry of phosphoryl group transfer using a chiral [16O, 17O, 18O] stereochemical course of alkaline phosphatase.
31P nuclear magnetic resonance spectra of the thiophosphate analogues of adenine nucleotides; effects of pH and Mg2+ binding.
Eileen K. Jaffe,Mildred Cohn +1 more