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Journal ArticleDOI

Stereochemical course of glycerol kinase, pyruvate kinase, and hexokinase: phosphoryl transfer from chiral [.gamma.(S)-16O,17O,18O]ATP

Walter A. Blaettler, +1 more
- 01 Jan 1979 - 
- Vol. 101, Iss: 2, pp 510-511
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This article is published in Journal of the American Chemical Society.The article was published on 1979-01-01. It has received 35 citations till now. The article focuses on the topics: Pyruvate kinase & Pyruvate dehydrogenase kinase.

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Journal ArticleDOI

Stereochemical course of phosphokinases. The use of adenosine [gamma-(S)-16O,17O,18O]triphosphate and the mechanistic consequences for the reactions catalyzed by glycerol kinase, hexokinase, pyruvate kinase, and acetate kinase.

TL;DR: It is shown that glycerol kinase and acetate kinase proceed by pathways that result in inversion of the configuration at phosphorus, which provides an access to the otherwise cryptic events that are involved in phosphoryl-group transfer within the ternary complexes of these kinases and their substrates.
Journal ArticleDOI

Stereochemistry of hydrolysis of adenosine 3':5'-cyclic phosphorothioate by the cyclic phosphodiesterase from beef heart.

TL;DR: Adenosine 3':5'-cyclic phosphorothioate, Sp-diastereomer was hydrolyzed by cyclic phosphodiesterase from beef heart in the presence of [18O]water to [ 18O]adenosine 5'-phosphorothIOate, and the result indicates that the hydrolysis proceeded with inversion of configuration at phosphorus.
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