Journal ArticleDOI
Stimulation of mouse bone marrow colony growth in vitro by conditioned medium.
T. R. Bradley,Margaret A Sumner +1 more
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This article is published in Immunology and Cell Biology.The article was published on 1968-10-01. It has received 147 citations till now. The article focuses on the topics: Bone marrow.read more
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Journal ArticleDOI
Conditions controlling the proliferation of haemopoietic stem cells in vitro.
TL;DR: A liquid culture system is described whereby proliferation of haemopoietic stem cells, production of granulocyte precursor cells (CFU‐C), and extensive granulopoiesis can be maintained in vitro for several months.
Journal ArticleDOI
Human bone marrow colony growth in agar-gel.
TL;DR: A technique for growing human bone marrow cell colonies in agar-gel medium is described in this paper, where feeder layers containing 1 × 106 normal human peripheral white blood cells are used as the stimulus for colony growth.
Journal ArticleDOI
Ontogeny of the haemopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo.
TL;DR: The mouse yolk sac has been shown to contain in‐vivo colony forming cells capable of producing granulocytic, megakaryocytic and erythroid spleen colonies, and haemopoietic precursor cells demonstrated in the blood at the time of initiation of the circulation and in the early embryonic liver.
Journal ArticleDOI
Erythroid colony formation in cultures of mouse and human bone marrow: analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-concanavalin A.
TL;DR: A simplification of the culture method for mouse bone marrow cells originally reported by Stephenson et al. ('71) is described, and with additional modification the system proved applicable to the culture of erythroid colonies from human bone marrow as well.
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