Journal ArticleDOI
Streptococcus pneumoniæ resistant to penicillin and chloramphenicol
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TLDR
In this article, three cases of meningitis and two cases of septicaemia were caused by pneumococci resistant to the penicillins/cephalosporins and chloramphenicol.About:
This article is published in The Lancet.The article was published on 1977-11-12. It has received 296 citations till now. The article focuses on the topics: Penicillin & Chloramphenicol.read more
Citations
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Journal ArticleDOI
Antimicrobial Resistance in Streptococcus pneumoniae: An Overview
TL;DR: Pneumococcal resistance has been described in Zambia, Japan, Malaysia, Pakistan, Bangladesh, Chile, and Brazil; information from other African, Asian, and South American countries is not available.
Journal ArticleDOI
Antimicrobial resistance in developing countries.
TL;DR: Better access to diagnostic laboratories is needed, as well as improved surveillance of the emergence of resistance, better regulation of antibiotics' use, and better education of the public, physicians, and veterinarians in the appropriate use of drugs.
Journal ArticleDOI
Resistance to penicillin and cephalosporin and mortality from severe pneumococcal pneumonia in Barcelona, Spain.
Roman Pallares,Josefina Liñares,Miquel Vadillo,Carmen Cabellos,Frederic Manresa,Pedro F. Viladrich,Rogelio Martín,Francesc Gudiol +7 more
TL;DR: Current levels of resistance to penicillin and cephalosporin by S. pneumoniae are not associated with increased mortality in patients with pneumococcal pneumonia, and these antibiotics remain the therapy of choice for this disease.
Journal ArticleDOI
Emergence of multiply resistant pneumococci.
Michael R. Jacobs,Hendrik J. Koornhof,Roy M. Robins-Browne,C M Stevenson,Z A Vermaak,I Freiman,G B Miller,M A Witcomb,M Isaäcson,J. I. Ward,R Austrian +10 more
TL;DR: Carriers of Types 6A and 19A penicillin-resistant pneumococci, resistant to antibiotic concentrations ranging between 0.12 and 4 microgram per milliliter were found in 29 of 543 pediatric patients and 2 of 434 hospital staff members in Johannesburg in July, 1977.
Journal ArticleDOI
The Spread of Multiply Resistant Streptococcus pneumoniae at a Day Care Center in Ohio
Mary R. Reichler,Allan A. Allphin,Robert F. Breiman,John R. Schreiber,James E. Arnold,Linda K. McDougal,Richard R. Facklam,Bernard Boxerbaum,Daniel May,Robert O. Walton,Michael R. Jacobs +10 more
TL;DR: Streptococcus pneumoniae, type 23F, resistant to penicillin and multiple other antimicrobic agents, was isolated from middle ear fluid of a child with otitis media attending a day care center in Ohio and carriers were more likely to have had frequent otitisMedia episodes.
References
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Book
Manual of clinical microbiology
TL;DR: A collaborative team of editors and authors from around the world revised the Manual to include the latest applications of genomics and proteomics, producing an authoritative work of two volumes filled with current findings regarding infectious agents, leading-edge diagnostic methods, laboratory practices, and safety guidelines.
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Novel Method for Detection of β-Lactamases by Using a Chromogenic Cephalosporin Substrate
TL;DR: A new cephalosporin with a highly reactive β- lactam ring was found to give an immediate color change in the presence of β-lactamases from many bacteria, including staphylococci, Bacillus species, Enterobacteriaceae, and Pseudomonas.
Book
Antibiotic and chemotherapy
TL;DR: Part 1: Aminoglycosides and aminocyclitols, Francis O'Grady antifungal agents, David C.Speller antimycobacterial agents, FrancisO' grady antiviral agents, Karl G.Nicholson part 2: General principles, Harold P.Lambert antimicrobial therapy in the immunocompromised host.
Journal ArticleDOI
Iodometric assay of penicillinase.
C. J. Perret,C. J. Perret +1 more
TL;DR: The series of iodometric methods reported here permits enzyme activity to be measured easily over wide ranges of pH and temperature, with higher speed, accuracy or sensitivity than were previously attainable, for penicillinase of B. cereus NRRL-569.