Structural studies on inclusion compounds and solvent sorption behavior of gradually elongated wheel-and-axle-type diol hosts featuring lateral benzo[b]thiophene units

TLDR: Based on the wheel-and-axle design strategy, a series of six clathrate hosts featuring two di(benzo[b]thien-2-yl)hydroxymethyl units attached to both ends of a central linear building element of varying length have been synthesized and their capability to form crystalline inclusion compounds with a fixed range of organic solvents are reported.

About: This article is published in Journal of Molecular Structure.The article was published on 2016-06-15 and is currently open access. It has received 6 citations till now. The article focuses on the topics: Sorption & Hydroxymethyl.

Figures

Fig. 2. Synthesis of the host compounds 1, 3 and 6.

Fig. 7. Illustration of the structure 2b: (a) Host molecule chain showing twofold disorder of the hydroxyl group. (b) Channel-like packing structure in the crystallographic b-direction and respective Van-der-Waals model. Non-relevant H-atoms were omitted for clarity.

Fig. 3. Synthesis of the host compounds 2, 4 and 5.

Fig. 12. Vapor absorption diagrams of the hosts 1 - 5 in comparison with BTh1 and BTh2 (a) as well as of the host 6 coated from different solvents (b).

Fig. 4. Molecular structures of the studied inclusion compounds 1a (a), 2a (b), 2b (c), 4a (d), 4b (e), 4c (f) and 5a (g) involving atom numbering scheme and specification of disorder sites in 1a, 2a, 4a, 4b, 4c and 5a. (Ellipsoid plots drawn with 50 % probability level.)

Table 4 Packing properties of the crystalline inclusion compounds.

Frequently asked questions

Q1. What have the authors contributed in "Structural studies on inclusion compounds and solvent sorption behavior of gradually elongated wheel-and-axle-type diol hosts featuring lateral benzo[b]thiophene units" ?

In this paper, it is shown that the covalently linked axis of a conventional wheel-and-axle host molecule can be replaced by a system of hydrogen bonds or by coordination of ligands generating inclusions alike.