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Study of rosin glycerol esters as microencapsulating materials.

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TLDR
The results showed that rosin and rosin-glycerol intermediates with acid values of 122, 105 and 55 had excellent moisture protection properties and could be used for delayed release of drug.
Abstract
Rosin esters were prepared by heating rosin with glycerol and intermediate reaction products with different acid values were withdrawn. Salicylic acid granules were encapsulated using a 10 per cent solution of rosin esters in acetone. The coated microcapsules were evaluated for moisture absorption, flow properties and dissolution studies. The results showed that rosin and rosin-glycerol intermediates with acid values of 122, 105 and 55 had excellent moisture protection properties. Dissolution studies showed that these could be used for delayed release of drug.

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Citations
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Study of the biodegradation and in vivo biocompatibility of novel biomaterials.

TL;DR: The degradation of rosin-based biomaterials was examined in vitro in phosphate-buffered saline at pH 7.4 and in vivo in a subcutaneous rat model, showing slow in vitro degradation when compared with the in vivo rate.
Journal ArticleDOI

Preparation and evaluation of microcapsules using polymerized rosin as a novel wall forming material.

TL;DR: Particle size and release data analysis from five consecutive batches prepared in the laboratory indicated suitable reproducibility of the proposed solvent evaporation process and the Higuchi-order release pattern.
Journal ArticleDOI

Biodegradation Studies of Rosin-Glycerol Ester Derivative:

TL;DR: The results of all the studies showed that rosin glycerol ester undergoes biodegradation and follows surface erosion mechanism.
Journal ArticleDOI

Film coating and biodegradation studies of new rosin derivative

TL;DR: In this article, a new glycerol and maleic anhydride derivative of rosin (RGM) was synthesized and investigated for its film forming and coating properties.
Journal ArticleDOI

Influence of ultrasound irradiation on the intrinsic viscosity of guar gum-PEG/rosin glycerol ester nanoparticles.

TL;DR: The miscibility-improving effect of sub-300 nm GG-PEG/RE nanoparticles is clearly proven due to the ultrasonic effect, and the viscosity results reveal that the blend containing 1:2 was an optimum miscible blend.
References
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Journal ArticleDOI

Study of Rosin and Rosin esters as coating materials

TL;DR: In this article, aspirin granules were coated with solution of Rosin and Rosin esters in acetone, and the results showed that rosin-coated granules release less than 10% drug in gastric media in 3 days and more than 75% drug within 15 min in intestinal media.
Journal ArticleDOI

Effect of Adjuvants on Tackiness of Polyvinylpyrrolidone Film Coating

TL;DR: The addition of ethylcellulose and shellac eliminated the tackiness sometimes associated with polyvinylpyrrolidone coating due to the hygroscopicity of the film former and increased the resistance of the tablet to mechanical stress, did not significantly increase the weight of the tablets, and were physically acceptable after storage at 2 and 45°.
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