Journal ArticleDOI
Study of the Gelation Process of Polyethylene Oxidea -Polypropylene Oxideb -Polyethylene Oxidea Copolymer (Poloxamer 407) Aqueous Solutions
Reads0
Chats0
TLDR
The C-O-C stretching bands of infrared spectra were found to shift toward higher wavenumbers with sol-gel transition, indicating that hydrogen bonding is not the driving force for gelation, and a mechanism of gelation based on micelles packing and entanglements is suggested.About:
This article is published in Journal of Colloid and Interface Science.The article was published on 1997-06-15. It has received 259 citations till now. The article focuses on the topics: Poloxamer 407 & Differential scanning calorimetry.read more
Citations
More filters
Journal ArticleDOI
In situ-forming hydrogels--review of temperature-sensitive systems.
TL;DR: This manuscript focuses on aqueous polymeric solutions that form implants in situ in response to temperature change, generally from ambient to body temperature, and mainly reviews the characterization and use of polysaccharides, N-isopropylacrylamide copolymers, poly(ethylene oxide) (poloxamer) and itsCopolymers.
Journal ArticleDOI
Thermoresponsive hydrogels in biomedical applications.
Leda Klouda,Antonios G. Mikos +1 more
TL;DR: The scope of this paper is to review the aqueous polymer solutions that exhibit transition to gel upon temperature change and focuses mainly on hydrogels based on natural polymers as well as poly(ethylene glycol)-biodegradable polyester copolymers.
Journal ArticleDOI
A Review of Poloxamer 407 Pharmaceutical and Pharmacological Characteristics
TL;DR: New findings have demonstrated immuno-modulation and cytotoxicity-promoting properties of Poloxamer 407 revealing significant pharmacological interest and, hence, human trials are in progress to specify these potential applications.
Journal ArticleDOI
Stimuli-Responsive Polymeric Systems for Biomedical Applications
TL;DR: The general aspects of the different types of stimuli that can be used to modulate the response are reviewed mainly for the case of hydrogels and surfaces, based on natural‐origin or biodegradable macromolecules.
Journal Article
Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations.
José Juan Escobar-Chávez,Miriam López-Cervantes,Aarti Naik,Yogeshvar N. Kalia,David Quintanar-Guerrero,Adriana Ganem-Quintanar +5 more
TL;DR: Of these systems, Pluronic F-127 (PF-127) provides the pharmacist with an excellent drug delivery system for a number of routes of administration and is compatible with many different substances.
References
More filters
Journal ArticleDOI
Artificial skin I. Preparation and properties of Pluronic F-127 gels for treatment of burns
TL;DR: The preparation of block polymer surface-active agents derived solely from propylene oxide and ethylene oxide, and the physical properties of a nonionic surfactant of 12,500 molecular weight, Pluronic F-127, are presented.
Journal ArticleDOI
Structural study on the micelle formation of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer in aqueous solution
Kell Mortensen,Jan Skov Pedersen +1 more
TL;DR: The phase behavior of the triblock copolymers dissolved in water has been studied using SANS as discussed by the authors, and the structural properties have been studied as a function of polymer concentration and temperature.
Journal ArticleDOI
The aggregation behavior of poly-(oxyethylene)-poly-(oxypropylene)-poly-(oxyethylene)-block-copolymers in aqueous solution
TL;DR: Aqueous solutions of blockcopolymers, consisting of a polyoxypropyleneblock (POP) with polyoxyethylene-block (POE) at each side, were studied using surface and interfacial tension measurements, static and dynamic light scattering and smallangle neutron scattering techniques, electric birefringence, rheological and DSC-measurements as discussed by the authors.
Journal ArticleDOI
Micelle and Gel Formation in a Poly (ethylene oxide)/ Poly (propylene oxide)/ Poly (ethylene oxide) Triblock Copolymer in Water Solution. Dynamic and Static Light Scattering and Oscillatory Shear Measurements
TL;DR: In this article, the properties of aqueous solutions of low molecular weight triblock copolymers of PEO/PPO/PEO have been investigated, mainly by dynamic and static light scattering.