Journal ArticleDOI
Substituierte Isatin‐phenylimine
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TLDR
In this article, 5-Bromo-and 5-nitro-isatin condense with substituted anilines to isatin-3-(phenyl)-imines.Abstract:
5-Brom- und 5-Nitro-isatin kondensieren mit substituierten Anilinen zu Isatin-3-(phenyl)-iminen. 5-Brom-isatin-3-(phenyl und naphthyl)-imin werden auch durch Bromieren von Isatin-3-(phenyl und naphthyl)-imin erhalten. Bei Einsatz von o-Phenylendiamin erfolgt Ringschlus zu 5-Brom-bzw. 5-Nitro-6,11-diaza-5H-benzo[b]carbazol, wobei als Zwischenprodukt wahrscheinlich die entsprechenden Isatin-3-(o-amino-phenyl)-imine auftreten.
Substituted Isatin Phenylimines.
5-Bromo- and 5-nitro-isatin condense with substituted anilines to isatin-3-(phenyl)-imines. 5-Bromo-isatin-3-(phenyl- and naphthyl)-imine are obtained also by bromination of isatin-3-(phenyl- and naphthyl)-imine. The reaction with o-phenylenediamine gives ring closed 5-bromo-and 5-nitro-6,11-diaza-5H-benzo-[b]-carbazoles. The isatin-3-(o-aminophenyl)-imines may act as intermediates in this reaction.read more
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Journal ArticleDOI
Potential anticonvulsants. VII. Synthesis of 5′‐methylspiro[3H‐indole‐3,2′‐thiazolidine]‐2,4′(1H)‐diones
Milind Rajopadhye,Frank D. Popp +1 more
TL;DR: In this article, the Mannich condensation of thiolactic acid with isatin-3-imines has been used to give 1-substituted derivatives of 5′-Methyl-3′-phenyl-spiro, 3H-indole-3,2′-thiazolidine]-2,4′(1H)-dione.
Patent
Substituted aza-oxindole derivatives
TL;DR: Substituted aza-oxindole derivatives useful as cyclin dependent kinase II inhibitors, for preventing/reducing the severity of epithelial cytotoxicity side-effects induced by chemoptherapy and/or radiation therapy in a patient receiving such therapy as discussed by the authors.
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Synthesis of biologically important novel fluorinated spiro heterocycles under microwaves catalyzed by montmorillonite KSF
Kapil Arya,Anshu Dandia +1 more
TL;DR: In this paper, arylidienes of fluorinated spiro thiazolidines containing α,β-unsaturated function have been used as component of Micheal addition with equimolar amount of 2-aminopyridine (6a) to give novel fluorinated SPIRIN [indole-3,2′-pyrido[1,2-a]thiazolo[5,4-e]pyrimidines] (7) in a single step under microwaves in presence of montmorillonite KSF as solid support
Journal ArticleDOI
Synthesis of spiro[3H-indole-3,2′-tetrahydro-1,3-thiazine]-2,4′(1H)-diones
Milind Rajopadhye,Frank D. Popp +1 more
TL;DR: In this article, the title compounds have been prepared by cyclocondensation of 3-mercaptopropanoic acid with isat-in-3-imines.
Journal ArticleDOI
Reaction of o-phenylenediamine with isatins
TL;DR: In this article, the reaction of o-phenylenediamine with isatins in the general case leads to mixtures of indolo[2,3-b]quinoxalines, 3-(2'-aminophenyl)-2(1H)-quinoxalinones, and spiro[2H-benzimidazoline-2, 3'-indolin-2'-ones].
References
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Journal ArticleDOI
Über die indigoähnlichen Gruppen von blauen Farbstoffen aus Isatin
C. Liebermann,R. Krauss +1 more