Journal ArticleDOI
Symmetrical and unsymmetrical 2,6-dialkyl-1,1′-biaryls by combined catalysis of aromatic alkylation via palladacycles and Suzuki-type coupling
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TLDR
In this article, the title compounds are made readily accessible by a catalytic procedure, occurring under mild conditions, based on palladium-mediated ortho alkylation of aromatic iodides with alkyl bromides followed by reaction with arylboronic acids.About:
This article is published in Chemical Communications.The article was published on 2000-01-01. It has received 88 citations till now. The article focuses on the topics: Alkylation & Catellani reaction.read more
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Aryl-aryl bond formation one century after the discovery of the Ullmann reaction.
Journal ArticleDOI
Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope.
TL;DR: This review summarizes the development and scope of carboxylates as cocatalysts in transition-metal-catalyzed C-H functionalizations until autumn 2010 and proposes new acronyms, such as CMD (concerted metalationdeprotonation), IES (internal electrophilic substitution), or AMLA (ambiphilic metal ligand activation), which describe related mechanisms.
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Towards mild metal-catalyzed C–H bond activation
TL;DR: This critical review summarizes and discusses endeavours towards the development of mild C-H activation methods and wishes to trigger more research towards this goal.
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Secondary alkyl halides in transition-metal-catalyzed cross-coupling reactions.
Alena Rudolph,Mark Lautens +1 more
TL;DR: This Minireview summarizes selected examples of the use of secondary alkyl halides as electrophiles in cross-coupling reactions, with emphasis on the transition metals employed, the mechanistic pathways involved, and implications in terms of the stereochemical outcome of reactions.
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Organopalladium(IV) chemistry
TL;DR: The stoichiometric reactions of Pd(IV) complexes are described and their potential mechanism in catalytic reactions is discussed, leading to the design and development of novel reactions that could not be accessed by traditional Pd (0)/Pd(II) chemistry.
Related Papers (5)
A Complex Catalytic Cycle Leading to a Regioselective Synthesis of o,o′-Disubstituted Vinylarenes
A New Route to Fused Aromatic Compounds by Using a Palladium-Catalyzed Alkylation - Alkenylation Sequence This work was supported by the NSERC (Canada) and the University of Toronto. S.P. thanks the Fondation Bettencourt - Schueller for a postdoctoral fellowship.
Mark Lautens,S Piguel +1 more