Journal ArticleDOI
Symptomatic and asymptomatic apical periodontitis associated with red complex bacteria: clinical and microbiological evaluation
Alessio Buonavoglia,Francesca Latronico,Chiara Pirani,Maria Fiorella Greco,Marialaura Corrente,Carlo Prati +5 more
TLDR
Generally, RC bacteria were associated with pain and a higher frequency of intracanalar/intrasulcular pus drainage and should be suspected in the presence of particularly severe clinical pain and pus drainage.Abstract:
In this study, the association of red complex (RC) bacteria that include Treponema denticola, Tannerella forsythia and Porphyromonas gingivalis with acute, exacerbated or chronic apical periodontitis was evaluated. Seventy-one patients with periapical disease were evaluated by clinical examination and microbiological samples obtained from the root canals were analyzed by a polymerase chain reaction assay. Twenty-one (29.6%) samples were positive for RC bacteria, with T. denticola, T. forsythia and P. gingivalis being detected in 14 (19.7%), 10 (14.1%) and 6 (8.5%) samples, respectively. RC bacteria were mainly associated with acute apical periodontitis (29.2%) and phoenix abscess (63.2%), while they were only sporadically detected (7.1%) in patients with chronic apical periodontitis. Generally, RC bacteria were associated with pain and a higher frequency of intracanalar/intrasulcular pus drainage. Involvement of RC bacteria in symptomatic periapical disease should be suspected in the presence of particularly severe clinical pain and pus drainage.read more
Citations
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The extent of pyroptosis varies in different stages of apical periodontitis
TL;DR: Evaluation of the role of caspase-1 and pyroptosis in periapical periodontitis showed caspases contributed to AP inflammation and lesion and pyrptosis extent was in line with AP progression, in conclusion.
Journal ArticleDOI
Elevated Systemic Inflammatory Burden and Cardiovascular Risk in Young Adults with Endodontic Apical Lesions
Mauricio Garrido,Angélica M. Cárdenas,J. Astorga,Francisca Quinlan,Macarena Valdés,Alejandra Chaparro,Paola Carvajal,Pirkko J. Pussinen,Patricia Huamán-Chipana,Jorge E. Jalil,Marcela Hernández,Marcela Hernández +11 more
TL;DR: ALO is associated with the systemic inflammatory burden and cardiovascular risk determined by hsCRP, supporting a mechanistic link for cardiovascular diseases in young adults.
Journal ArticleDOI
Periodontopathogen and Epstein–Barr Virus‐Associated Periapical Periodontitis May Be the Source of Retrograde Infectious Peri‐Implantitis
Fernando Verdugo,Ana Castillo,Krikor Simonian,Francisca Castillo,Esther Farez-Vidal,Antonio D'Addona +5 more
TL;DR: If confirmed by prospective longitudinal clinical trials, antiviral therapy could possibly benefit SP and nonresponsive to treatment individuals and help prevent potential peri-implant infectious complications and help establish antimicrobial therapy.
Journal ArticleDOI
Periodontal disease associated with red complex bacteria in dogs
A. Di Bello,A. Buonavoglia,Delia Franchini,Carmela Valastro,Gianpiero Ventrella,Maria Fiorella Greco,Marialaura Corrente +6 more
TL;DR: It is indicated that involvement of red complex bacteria in periodontal disease in dogs is similar to that observed in humans.
Journal ArticleDOI
Complementary clinical effects of red complex bacteria on generalized periodontitis in a caucasian population.
Esperanza Lanza,Antonio Magán-Fernández,B Bermejo,J de Rojas,Rafael Marfil-Alvarez,Francisco Mesa +5 more
TL;DR: The prevalence of red complex bacteria was similar between aggressive and chronic periodontitis, but their count was higher in the former, and tobacco smoking was not associated with the presence ofred complex bacteria in either disease.
References
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Microbial complexes in subgingival plaque
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Oral and Maxillofacial Pathology
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Journal ArticleDOI
Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: The 'red complex', a prototype polybacterial pathogenic consortium in periodontitis
Journal ArticleDOI
Microbial status of apical root canal system of human mandibular first molars with primary apical periodontitis after “one-visit” endodontic treatment
TL;DR: The results show the anatomical complexity of the root canal system of mandibular first molar roots and the organization of the flora as biofilms in inaccessible areas of the canal system that cannot be removed by contemporary instruments and irrigation alone in one-visit endodontic treatment.
Journal ArticleDOI
Improved multiplex PCR using conserved and species-specific 16S rRNA gene primers for simultaneous detection of Actinobacillus actinomycetemcomitans, Bacteroides forsythus, and Porphyromonas gingivalis.
Simon D. Tran,Joel D. Rudney +1 more
TL;DR: The simultaneous detection of three periodontal pathogens is an advantage of this technique over conventional PCR assays.