Journal ArticleDOI
Synthesis and Structure of 2-Ethoxy- and 2-Aminomethylidene- 3-fluoroalkyl-3-oxopropionates
M. V. Pryadeina,Ya. V. Burgart,V. I. Saloutin,Pavel A. Slepukhin,Olga N. Kazheva,Gennadii V. Shilov,Oleg A. Dyachenko,Oleg N. Chupakhin +7 more
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TLDR
In this paper, the X-ray diffraction and IR data showed that 2-morpholino(pyrrolidin-1-yl)methylidene-3-fluoroalkyl-3 -oxopropionates exist as Z isomers both in the crystalline state and in solution.Abstract:
Condensation of ethyl 3-polyfluoroalkyl-3-oxopropionates with excess triethyl orthoformate gave ethyl 3-polyfluoroalkyl-2-ethoxymethylidene-3-oxopropionates which reacted with primary aliphatic, aromatic, and heterocyclic amines to form ethyl 2-alkyl(aryl, hetaryl)aminomethylidene-3-polyfluoroalkyl-3-oxopropionates. According to the X-ray diffraction and IR data, the latter exist in the crystalline state as the corresponding E isomers, while in solution (NMR data), as mixtures of Z and E isomers. Condensation of ethyl 2-ethoxymethylidene-3-oxopropionates with secondary heterocyclic amines (morpholine and pyrrolidine) led to the formation of 2-morpholino(pyrrolidin-1-yl)methylidene-3-fluoroalkyl-3-oxopropionates which were shown to exist as Z isomers both in the crystalline state and in solution.read more
Citations
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Journal ArticleDOI
Hypervalent Iodine(III) Promoted Direct Synthesis of Imidazo[1,2-a]pyrimidines
TL;DR: An efficient and mild synthesis of imidazo[1,2-a]pyrimidine derivatives has been developed from readily available pyrimidyl arylamines or enamines through a hypervalent iodine-promoted intramolecular C–H bond cycloamination reaction.
Journal ArticleDOI
The use of 2-(1-alkoxyalkylidene)-1,3-dicarbonyl compounds in organic synthesis
TL;DR: In this article, a review of the methods of synthesis of 2-(1-alkoxyalkylidene)-1,3-dicarbonyl compounds and their chemical transformations is presented.
Journal ArticleDOI
Synthesis, insecticidal activities and structure–activity relationship studies of novel anthranilic diamides containing pyridylpyrazole‐4‐carboxamide
TL;DR: Thirty-two new anthranlic diamides containing pyridylpyrazole-4-carboxamide were designed and obtained and SAR analysis and DFT calculation results revealed that the amide moiety had a very important effect on bioactivity.
Patent
Method for preparing 1,3,4-substituted pyrazol compounds
Bernd Wolf,Maywald Volker,Keil Michael,Christopher Koradin,Michael Rack,Thomas Zierke,Martin Sukopp +6 more
TL;DR: In this article, an Ethernet bridge or router comprising a network fabric adapted to provide interconnectivity to a plurality of Ethernet ports, each of the Ethernet ports being adapted to receive and/or transmit Ethernet frames, and the encapsulator is operable to transform Ethernet destination address information from the Ethernet protocol Data Unit into a routing definition for the network fabric, and to include this routing definition in the header portion of the Fabric Protocol Data Unit.
Journal ArticleDOI
Synthesis of fluoroalkylated dihydroazolo〔1,5-a〕pyrimidines and their ring-chain isomerism
TL;DR: In this article, a ring-chain isomerization of polyfluoroalkylated dihydroazolo[1,5-a]pyrimidines is described.
References
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Book
Applications of Dynamic Nmr Spectroscopy to Organic Chemistry
TL;DR: In this article, applications of dynamic NMR spectroscopy to organic chemistry are discussed. But the authors focus on the application of NMR to the organic chemistry domain, and do not consider the applications in the biomedical domain.
Journal ArticleDOI
Fluorine-containing β-Ketoesters
TL;DR: In this article, the methods of synthesis, the keto-enol tautomerism, chemical properties, and applications of fluorine-containing β-ketoesters are surveyed.
Journal ArticleDOI
Geometric isomerism in the series of fluoroalkyl-containing 1,2,3-trione 2-arylhydrazones
Olga G. Khudina,Evgeny V. Shchegolkov,Ya. V. Burgart,M. I. Kodess,Viktor I. Saloutin,Olga N. Kazheva,Gennady V. Shilov,Oleg A. Dyachenko,Maria Grishina,Vladimir Potemkin,Oleg N. Chupakhin +10 more
TL;DR: According to the 1H, 13C, and 19F NMR data, fluoroalkyl-containing 1,2,3-trione 2-arylhydrazones in CDCl3 exist exclusively, while in (CD3)2CO preferentially, as isomers in which the acyl or aroyl group is involved in intramolecular hydrogen bond as mentioned in this paper.
Journal ArticleDOI
Reaction of Fluoro-containing 3-Oxoesters with Benzaldehyde
TL;DR: Fluorinated 3-oxoesters in reactions with benzaldehyde depending on conditions afford either 2-benzylidene-3-fluoroalkyl-3oxoester or 3,5-dialkoxycarbonyl-2,6-dihydroxy-2.6-dimethylhexyl-4-phenyltetrahydropyrans.
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