Journal ArticleDOI
Synthesis, characterization, and biological applications of pyrazole moiety bearing osmium(IV) complexes.
Bharat H. Pursuwani,Bhupesh S. Bhatt,Dilip B. Raval,Vasudev R. Thakkar,Jyoti Sharma,Chandramani Pathak,Mohan N. Patel +6 more
TLDR
Osmium (IV) complexes with pyrazole nucleus containing ligands were synthesized in this article, where all the compounds were tested for their potential to interact with HS-DNA by absorption titration, fluorescence spectroscopy, viscosity measurement and docking study.Abstract:
Osmium (IV) complexes with pyrazole nucleus containing ligands were synthesized. Os(IV) compounds were characterized using ESI-MS, ICP-OES, IR spectroscopy, electronic spectroscopy, conductance, and magnetic measurements. Whereas, ligands were characterized by heteronuclear spectroscopy, (1H and 13C), IR spectroscopy, and elemental analysis. All the compounds were tested for their potential to interact with HS-DNA by absorption titration, fluorescence spectroscopy, viscosity measurement, and docking study. The quenching constant and Stern Volmer constant values were calculated using fluorescence study. The synthesized compounds were studied for in-vitro bacteriostatic and cytotoxic activities. The cancer cell line studies of all the synthesized complexes were carried out on human lung cancer cells (A549).Supplemental data for this article is available online at https://doi.org/10.1080/15257770.2021.1921795 .read more
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DNA interaction, antimicrobial, electrochemical and spectroscopic studies of metal(II) complexes with tridentate heterocyclic Schiff base derived from 2′-methylacetoacetanilide
TL;DR: In this article, a Schiff base ligand was synthesized by the condensation reaction between 2′-methyleacetoacetanilide and 2-amino-3-hydroxypyridine.
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Novel multinuclear transition metal(II) complexes based on an asymmetric Salamo-type ligand: Syntheses, structure characterizations and fluorescent properties
TL;DR: In this paper, three multinuclear complexes with an asymmetric Salamo-type ligand H 4 L were synthesized with FT-IR, UV-vis spectra and X-ray crystallography.
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Phytochemicals: Current strategy to sensitize cancer cells to cisplatin.
TL;DR: This review discussed the progress made in utilizing phytochemicals to enhance the anti-cancer efficacy of cisplatin and presented some ideal phytochemicalicals as novel agents for counteracting cis platin-induced organ damage.
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Evaluation of DNA binding, antioxidant and cytotoxic activity of mononuclear Co(III) complexes of 2-oxo-1,2-dihydrobenzo[h]quinoline-3-carbaldehyde thiosemicarbazones.
Eswaran Ramachandran,Sajesh P. Thomas,Paramasivan Poornima,P. Kalaivani,Rathinasabapathi Prabhakaran,V. Vijaya Padma,Karuppannan Natarajan +6 more
TL;DR: Four new 2-oxo-1,2-dihydrobenzo[h]quinoline-3-carbaldehyde N-substituted thiosemicarbazone ligands and their corresponding new cobalt(III) complexes have been synthesized and characterized and showed significant antioxidant activity against DPPH radical.
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Recent advances in boron-centered ligands and their transition metal complexes
TL;DR: Boron-centered transition metal ligands as mentioned in this paper have been used as strong σ-donors, π-donor and acceptors, making them versatile ligands for transition metal centers.