Journal ArticleDOI
Synthesis of glycosides of fucose under neutral conditions in solutions of LiClO4 in organic solvents
Gerd Böhm,Herbert Waldmann +1 more
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TLDR
In this paper, the glycosyl donors 2,3,4-tri-O-benzyl fucosyl fluoride and trichloroacetimidate are activated under neutral conditions in 1M solutions of LiClO 4 in CH 2 Cl 2 or ether to react with mono- and disaccharides to give fucoseyl glycosides in high yields and with high stereoselectivity.About:
This article is published in Tetrahedron Letters.The article was published on 1995-05-29. It has received 36 citations till now. The article focuses on the topics: Glycosyl & Ether.read more
Citations
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Journal ArticleDOI
Catalytic Glycosylations in Oligosaccharide Synthesis
TL;DR: All methods of catalytic glycosylation with the focus on the development and application in oligosaccharide synthesis and an overview of the scope and limitations of these are provided.
Journal ArticleDOI
Explorations into new reaction chemistry.
TL;DR: The basic concepts that have guided the exploration of new chemical reactions by giving examples of results from my research group are described, and it can be said that by reviewing what the authors had done before, they were able to expand on it to achieve new outcomes.
Journal ArticleDOI
Glycosyl fluorides in glycosidations.
TL;DR: Several types of C-glycosyl compounds, such as aryl, allyl and alkyl C- Glycosyl derivatives, were also obtained by the glycosylation using gly cosyl fluorides and the corresponding nucleophile with or without a Lewis acid.
Journal ArticleDOI
Recent developments in polymer supported syntheses of oligosaccharides and glycopeptides
TL;DR: A review of methods available for the polymer supported syntheses of oligosaccharides and glycopeptides is presented in this paper, where a range of polymers and linkers, and analytical techniques employed in recent syntheses are described.
Journal ArticleDOI
Perchloric acid and its salts: very powerful catalysts in organic chemistry
TL;DR: A comparison of ring-Opening Reactions and Multicomponent Reactions shows the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for humans and animals.
References
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Journal ArticleDOI
Biological roles of oligosaccharides: all of the theories are correct
TL;DR: The only common features of the varied functions of oligosaccharides are that they either mediate ‘specific recognition’ events or that they provide ‘modulation’ of biological processes.
Journal ArticleDOI
Selectins: interpreters of cell-specific carbohydrate information during inflammation.
TL;DR: The biology of these carbohydrate-binding adhesive proteins are reviewed and the potential for developing anti-inflammatory antagonists that could inhibit binding events that are selectin-mediated is discussed.
Journal ArticleDOI
New Methods for the Synthesis of Glycosides and Oligosaccharides—Are There Alternatives to the Koenigs‐Knorr Method? [New Synthetic Methods (56)]
TL;DR: Emphasis is placed on glycoside and saccharide formation by 1-O-alkylation, on the trichloroacetimidate method, and on activation through the formation of glycosylsulfonium salts and Glycosyl fluorides.
Journal ArticleDOI
Demonstration by Monoclonal Antibodies That Carbohydrate Structures of Glycoproteins and Glycolipids Are Onco-Developmental Antigens
TL;DR: These findings either may reflect limitations in the methods of selection of hybridoma antibodies or point to important roles for the diverse carbohydrate structures as receptors for regulators of cell growth and differentiation.
Book ChapterDOI
Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens
TL;DR: Aberrant glycosylation as such may be the basis of inappropriate cell/cell and cell/matrix interactions that may be reflected in the abnormal cell social behavior of tumor cells, such as uncontrolled cell growth, invasiveness, and metastatic potential.
Related Papers (5)
New Methods for the Synthesis of Glycosides and Oligosaccharides—Are There Alternatives to the Koenigs‐Knorr Method? [New Synthetic Methods (56)]
Recent progress in O-glycosylation methods and its application to natural products synthesis
Kazunobu Toshima,Kuniaki Tatsuta +1 more