Journal ArticleDOI
Synthetic and biological studies on coumarin hydrazone derivatives
TLDR
The reaction of coumarin and 6-nitrocoumarin hydrazones (1,4) with alkyl(aryl)isothiocyanate afforded the corresponding 3-N[alkyl (aryl)thioamido] coumarins 3a-d or benzopyrano[2,3-c]pyrazole-3-thione derivatives 6a-D, respectively as mentioned in this paper.Abstract:
The reaction of both of coumarin and 6-nitrocoumarin hydrazones (1,4) with alkyl(aryl)isothiocyanate afforded the corresponding 3-N[alkyl(aryl)thioamido] coumarins 3a-d or benzopyrano[2,3-c]pyrazole-3-thione derivatives 6a-d , respectively. Compounds (3a-d) were used as key intermediates for the preparation of benzopyrano-pyridine derivatives (7a-d & 10a) or benzopyranoazepine derivatives 8a,c & 12a-d through the reaction with different acyl halides or ethoxymethylenemalononitriles and subsequent cyclization. Biological activity of some new compounds against Gram +ve and Gram -ve were given.read more
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Journal ArticleDOI
Synthesis and Biological Evaluation of Some New Coumarin Derivatives
TL;DR: Pyridino and pyrrolo as discussed by the authors were used to synthesize new compounds featuring different heterocyclic rings fused onto the coumarin moiety with the aim of obtaining more potent pharmacologically active compounds.
Journal ArticleDOI
Synthesis, spectral characterization and antimicrobial evaluation of Schiff base Cu (II), Ni (II) and Co (II) complexes.
TL;DR: Electronic and magnetic moments of the complexes indicate that the geometries of the metal centers are either distorted octahedral, or square planer.
Journal ArticleDOI
Synthesis, spectral characterization and antimicrobial evaluation of Schiff base Cr (III), Mn (III) and Fe (III) macrocyclic complexes.
TL;DR: A Schiff base ligand was synthesized by reacting 1,4-dicarbonyl-phenyl-dihydrazide and chromene-2,3-dione and a series of metal complexes with this new ligand and its metal complexes were tested for their antimicrobial activities and for their inhibiting potential.
Journal ArticleDOI
Coordination chemistry of rare earth metal complexes with coumarin-based imines: ecofriendly synthesis, characterization, antimicrobial, DNA cleavage, pesticidal, and nematicidal activity evaluations
TL;DR: In this paper, the coordination and biocidal aspects of lanthanide(III) complexes with 3-formyl-4-chlorocoumarin hydrazinecarbothioamide (L1H) and 3 -formyl 4-chloro-marin hydranecarboxamide (H2H) are described with the support of elemental analyses, molecular weight, melting point, and molar conductance determinations along with the IR, 1H NMR, EPR, UV spectral, and X-ray powder diffraction studies.
Journal ArticleDOI
Synthesis and characterization of some transition metal complexes with a novel Schiff base ligand and their use as catalysts for olefin cyclopropanation
TL;DR: In this article, a novel ligand HL (1), N,2-bis(1-(2-oxo-2H-chromen-3-yl)ethylidene)hydrazinecarbothioamide was synthesized through the condensation of 3-acetyl-2-hexyl-hexylon-hexen-2.1 and hydrazine-carbothion.
References
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Journal ArticleDOI
Synthesis of some new biologically-active coumarin derivatives
TL;DR: Alternative procedures, other reactions and biological activity of some new compounds were given and some alkylation, acylation and Mannich reactions were studied.
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A Novel Synthesis of 4-Aminomethylcoumarins
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Convenient synthesis of 5-azacoumarins
TL;DR: In this paper, 2-Formyl-3-hydroxypyridine and its 6-methyl derivative have been condensed with ethoxycarbonylmethyl-enetriphenylphosphorane and alkyl derivatives to afford 5-azacoumarins substituted in the second case by an alkyal group at 3 position by two different ways according to the used phosphorane.
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Synthesis of Some New Spiro Heterocycles from the Reaction of 2-Coumarylidenemalononitrile with Active Methylene and Bidentate Reagents
TL;DR: The 2-Coumarylidenemalononitriles 1a,b with some active methylene, bidentates and ketoketene S, S or N, S acetals affords a series of new spiro heterocyclic systems.