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Tetrahedron report number 190

I. Paterson, +1 more
- 01 Jan 1985 - 
- Vol. 41, Iss: 18, pp 3569-3624
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This article is published in Tetrahedron.The article was published on 1985-01-01. It has received 229 citations till now. The article focuses on the topics: Tetrahedron.

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C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals

TL;DR: This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.
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Funktionalisierung von C‐H‐Bindungen: neue Synthesemethoden für Naturstoffe und Pharmazeutika

TL;DR: In this paper, aufsatz gibt einen Uberblick uber die Strategien, die durch Funktionalisierung von C-H-Bindungen eine rasche Synthese von biologisch aktiven Verbindungen wie Naturstoffen und pharmazeutischen Zielsubstanzen ermoglichen.
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Modern aldol methods for the total synthesis of polyketides.

TL;DR: This Review illustrates by means of selected syntheses of natural products the new variants of the aldol addition, which includes a Aldol additions with various metal enolates, as well as metal-complex-catalyzed, organocatalytic, and biocatalysis methods.
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A comprehensive review of glycosylated bacterial natural products.

TL;DR: This comprehensive analysis of 15 940 bacterial natural products revealed 3426 glycosides containing 344 distinct appended carbohydrates and highlights a range of unique opportunities for future biosynthetic study and glycodiversification efforts.
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PatentDOI

First practical method for asymmetric epoxidation

TL;DR: In this article, a metal alkoxide is used as a catalyst, where the metal has a coordination number of at least four, and at least one, usually two, of the alkoxide groups bonded to the metal are bonded to asymmetric carbon atoms.
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A rapid esterification by means of mixed anhydride and its application to large-ring lactonization.

TL;DR: In this paper, a rapid and mild esterification method using carboxylic 2,4,6-trichlorobenzoic anhydrides in the presence of 4-dimethylaminopyridine was developed.