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Journal ArticleDOI

The action of bemegride on presynaptic inhibition

N.R. Banna, +1 more
- 01 Nov 1970 - 
- Vol. 9, Iss: 6, pp 553-560
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TLDR
It is concluded that bemegride, like picrotoxin, blocks depolarization of presynaptic terminals of muscle and ascending cutaneous primary afferent fibres, and thus reduces Presynaptic inhibition.
About
This article is published in Neuropharmacology.The article was published on 1970-11-01. It has received 15 citations till now. The article focuses on the topics: Cuneate nucleus & Bemegride.

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Citations
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Book ChapterDOI

Control of the Access of Afferent Activity to Somatosensory Pathways

TL;DR: The central nervous system of a mammal, or any other vertebrate for that matter, is continuously exposed to a barrage of afferent impulses coming from the receptors of its various sense organs, and is forced to adapt its input sensitivity to the range of the peripheral stimuli by inhibiting the inflow: the greater the afferent inflow, the more the inhibition.
Journal ArticleDOI

PRESYNAPTIC ACTIONS OF β-AMINOBUTYRIC ACID AND SOME ANTAGONISTS IN A SLICE PREPARATION OF CUNEATE NUCLEUS

TL;DR: Responses to high concentrations of GABA were sometimes potentiated by (+)‐biculline and strychnine, but with low potency and in a manner which was clearly not competitive.
Journal ArticleDOI

ANTAGONISM OF γ‐AMINOBUTYRIC ACID AND GLYCINE BY CONVULSANTS IN THE CUNEATE NUCLEUS OF CAT

TL;DR: It is concluded that the selective glycine antagonist strychnine is considerably better than the presently available GABA antagonists for distinguishing between responses to GABA and glycine, when the antagonists are applied by microiontophoresis.
Journal ArticleDOI

Processing of sensory information.

TL;DR: This review has, unless forced to go elsewhere for an illustrative example, been concerned solely with the transfer of information from the face and for the visual and auditory systems.
References
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Journal ArticleDOI

The physiology of synapses

Journal ArticleDOI

Pharmacological studies on presynaptic inhibition

TL;DR: Physiological investigations on presynaptic inhibition have led to the hypothesis that it is effected by chemically transmitting synapses that impinge on the terminal knobs of excitatory synapses and exert a depolarizing action thereon.
Journal ArticleDOI

Presynaptic inhibition of the spinal monosynaptic reflex pathway.

TL;DR: The results of the present study show that there is a powerful and prolonged depression of the monosynaptic reflex discharge; and arguments are presented that the reflex depression observed is due to presynaptic inhibition.
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