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The blood supply of experimental liver metastases. II. A microcirculatory study of the normal and tumor vessels of the liver with the use of perfused silicone rubber.

W M Lien, +1 more
- 01 Aug 1970 - 
- Vol. 68, Iss: 2, pp 334-340
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This article is published in Surgery.The article was published on 1970-08-01 and is currently open access. It has received 192 citations till now. The article focuses on the topics: Microcirculation.

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What is the evidence that tumors are angiogenesis dependent

TL;DR: Method of treating a wound or burn which comprises directly dressing its surface with non-woven fabric comprising staple fibers of spun, regenerated collagen substantially free of telopeptides is disclosed.
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How tumors become angiogenic

TL;DR: Although the importance of angiogenesis to the growth of tumors is now well established, the mechanism by which tumor cells develop this crucial ability to attract new blood vessels is just beginning to be explored.
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A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases.

TL;DR: A small gain in survival seen in a select subgroup of patients with negative hepatic nodes appeared to be offset by the toxicity of I.A.V. FUDR, which allowed more drug delivery to liver tumors, which resulted in increased tumor responses when compared with use of systemic therapy.
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Pathologic response and microdosimetry of 90Y microspheres in man: Review of four explanted whole livers

TL;DR: An analysis of 4 explanted livers previously treated with (90)Y microsphere agents, finding preferential and heterogeneous deposition of microspheres was noted at the edge of tumor nodules compared with the center portion of the tumor or normal liver parenchyma.
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