Open AccessJournal Article
The Carcinogenicity of Essential Oils, Flavors, and Spices: A Review
F Homburger,Eliahu Boger +1 more
TLDR
This paper summarizes knowledge on the carcinogenic activity of safrole, citrus oils, turpentine oil, eucalyptus oil (phellandrene), bergamot oil, and red pepper and the possible role of polycyclic hydrocarbons biosynthesized in plants is discussed.Abstract:
Summary Essential oils, flavors, and spices constitute a large and heterogeneous groups of substances to which humans are exposed. The essential oils are defined as a group of odorous principles soluble in alcohol and only to a limited extent in water. They consist of a mixture of esters, aldehydes, ketones, and terpenes. Relatively few members of this group of substances have been shown to cause cancer in animals. This paper summarizes knowledge on the carcinogenic activity of safrole, citrus oils ( d -limonene), turpentine oil ( l -pinene), eucalyptus oil (phellandrene), bergamot oil, and red pepper. The possible role of polycyclic hydrocarbons biosynthesized in plants is also discussed.read more
Citations
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Metabolic interactions among environmental chemicals and drugs.
Allan H. Conney,J. J. Burns +1 more
TL;DR: Research into metabolic interactions among drugs, insecticides, food additives, carcinogenic hydrocarbons, and a variety of environmental chemicals provides information that is helpful in the evaluation of the safety and efficacy of drugs and environmental chemicals, and suggests new directions for further research.
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Naturally Occurring Food Toxins
TL;DR: The purpose of this review is to provide a toxicological and regulatory overview of some of the toxins present in some commonly consumed foods, and to discuss the steps that have been taken to reduce consumer exposure, many of which are possible because of the unique process of food regulation in the United States.
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Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay
Azliyati Azizan,R. D. Blevins +1 more
TL;DR: It was inferred that chlorophyll can successfully suppress the mutagenicity activities of capsaicin and 2-aminoanthracene, together with other antimutagenic factors that were present in the acetone extract of C. annum.
Journal ArticleDOI
Induction of Benzo[α]pyrene Hydroxylase in Human Skin
TL;DR: An evaluation of the basal activity and inducibility of carcinogen-metabolizing enzymes in human tissues may provide a means of determining the ability of different individuals to metabolize carcinogens.
References
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Journal ArticleDOI
Carcinogenicity of Epoxides, Lactones, and Peroxy Compounds
Journal ArticleDOI
The experimental disclosure of latent neoplastic changes in tarred skin.
Ian MacKenzie,Peyton Rous +1 more
TL;DR: The ability of tumor cells to lie latent for long periods and respond to non-carcinogenic stimulation by multiplying into growths provides an explanation of those clinical instances in which cancer appears rapidly after acute injury to tissue that had seemed normal.
Journal Article
Studies on the promoting phase in the stages of carcinogenesis in mice, rats, rabbits, and guinea pigs.
TL;DR: Wound healing alone has been found to be an effective stimulus and the specific effect of croton oil on the mouse and of wound healing on the rabbit, as promoters of tumor formation are discussed.