The challenge of dry eye diagnosis
Giacomo Savini,Pinita Prabhawasat,Takashi Kojima,Martin Grueterich,Edgar M. Espana,Eiki Goto +5 more
TLDR
This review attempts to highlight the advantages and disadvantages of both traditional tests and innovative noninvasive procedures for the diagnosis of dry eye, including tear meniscus height measurement, corneal topography, functional visual acuity, tear interferometry, tear evaporimetry and tear osmolarity assessment.Abstract:
The currently available methods for the diagnosis of dry eye are still far from being perfect for a variety of reasons. This review attempts to highlight the advantages and disadvantages of both traditional tests (such as Schirmer’s test, break-up time and ocular surface staining) and innovative noninvasive procedures, including tear meniscus height measurement, corneal topography, functional visual acuity, tear interferometry, tear evaporimetry and tear osmolarity assessment.read more
Citations
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TFOS DEWS II Epidemiology Report.
Fiona Stapleton,Monica Alves,Vatinee Y Bunya,Isabelle Jalbert,Kaevalin Lekhanont,Florence Malet,Kyung Sun Na,Debra A. Schaumberg,Miki Uchino,Jelle Vehof,Eloy Viso,Susan Vitale,Lyndon Jones +12 more
TL;DR: The subcommittee reviewed the prevalence, incidence, risk factors, natural history, morbidity and questionnaires reported in epidemiological studies of dry eye disease and confirmed that prevalence increases with age, however signs showed a greater increase per decade than symptoms.
Journal ArticleDOI
TFOS DEWS II Management and Therapy Report
Lyndon Jones,Laura E Downie,Donald R. Korb,Jose M. Benitez-del-Castillo,Reza Dana,Sophie X. Deng,Pham N. Dong,Gerd Geerling,Richard Y Hida,Yang Liu,Kyoung Yul Seo,Joseph Tauber,Tais Hitomi Wakamatsu,Jianjiang Xu,James S. Wolffsohn,Jennifer P. Craig +15 more
TL;DR: It became clear that many of the treatments available for the management of dry eye disease lack the necessary Level 1 evidence to support their recommendation, often due to a lack of appropriate masking, randomization or controls and in some cases due to issues with selection bias or inadequate sample size.
Journal ArticleDOI
Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study.
TL;DR: The proportion of subjects exhibiting signs of evaporative dry eye resulting from MGD far outweighs that of subjects with pure ADDE in a general clinic-based patient cohort.
Journal ArticleDOI
Diagnosing the severity of dry eye: a clear and practical algorithm
Christophe Baudouin,Pasquale Aragona,Gysbert van Setten,Maurizio Rolando,Murat Irkec,Jose M. Benitez del Castillo,Gerd Geerling,Marc Labetoulle,Stefano Bonini +8 more
TL;DR: A consensus-based algorithm for DED evaluation is presented, which facilitates diagnosis of severe disease even in the event of discordance between signs and symptoms, and is intended that this algorithm will be useful in a clinical and developmental setting.
Journal ArticleDOI
Associations between signs and symptoms of dry eye disease: a systematic review.
TL;DR: This article conducted a systematic literature review to evaluate published studies reporting associations between patient-reported symptoms and clinical signs of dry eye disease (DED) and found that changes and severity of clinical signs often do not correspond to patientreported symptoms.
References
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Journal ArticleDOI
Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group
Claudio Vitali,Stefano Bombardieri,Roland Jonsson,Haralampos M. Moutsopoulos,E L Alexander,Steven E. Carsons,Troy E. Daniels,P C Fox,Robert I. Fox,Stuart S. Kassan,S R Pillemer,Norman Talal,M H Weisman +12 more
TL;DR: These classification criteria for Sjögren's syndrome have been re-examined by consensus group members, who have introduced some modifications, more clearly defined the rules for classifying patients with primary or secondary SS, and provided more precise exclusion criteria.
Journal ArticleDOI
The definition and classification of dry eye disease: Report of the definition and classification subcommittee of the international Dry Eye WorkShop (2007)
Michael A. Lemp,Christophe Baudouin,Jules L. Baum,Murat Dogru,Gary N. Foulks,Shigeru Kinoshita,Peter R. Laibson,James P. McCulley,Juan Murube,Stephen C. Pflugfelder,Maurizio Rolando,Ikuko Toda +11 more
TL;DR: A new definition of dry eye was developed to reflect current understanding of the disease, and a three-part classification system was recommended, based on the severity of the dry eye disease, which is expected to provide a rational basis for therapy.
Journal ArticleDOI
Reliability and validity of the Ocular Surface Disease Index.
TL;DR: The OSDI is a valid and reliable instrument for measuring the severity of dry eye disease, and it possesses the necessary psychometric properties to be used as an end point in clinical trials.
Journal Article
Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes.
Journal ArticleDOI
Grading of corneal and conjunctival staining in the context of other dry eye tests.
TL;DR: The monitoring and assessment of corneal and conjunctival staining can be greatly enhanced by the use of a grading scale, controlled instillation of dyes, and standard evaluation techniques.