Journal ArticleDOI
The Comprehensive Assessment of Symptoms and History (CASH). An instrument for assessing diagnosis and psychopathology.
TLDR
Research strategies suggest that investigators should maintain a flexible database to permit them to adapt to changes in diagnostic systems, to do comparative nosological studies, and, ultimately, to develop new diagnostic systems based on knowledge concerning the underlying neurobiological nature of disorders.Abstract:
• The Comprehensive Assessment of Symptoms and History was developed for research studies of schizophrenia spectrum conditions and affective spectrum conditions. It is designed to provide a comprehensive information base concerning current and past signs and symptoms, premorbid functioning, cognitive functioning, sociodemographic status, treatment, and course of illness. Because the information base is broad, it is not wedded to a specific diagnostic system but rather permits clinicians and investigators to make diagnoses using a wide range of systems, including Research Diagnostic Criteria,DSM-III, DSM-III-R, and theInternational Classification of Diseases. Given the fact that disorders in psychiatry are not defined at the etiological or pathophysiological level, diagnostic criteria are prone to ongoing revision as our knowledge base changes. Research strategies suggest that investigators should maintain a flexible database to permit them to adapt to changes in diagnostic systems, to do comparative nosological studies, and, ultimately, to develop new diagnostic systems based on knowledge concerning the underlying neurobiological nature of disorders. Because it provides a comprehensive information base, the Comprehensive Assessment of Symptoms and History facilitates research of this type. Extensive developmental work has been done with the Comprehensive Assessment of Symptoms and History, including interrater and test-retest reliability studies, validity studies, training programs, and data entry programs.read more
Citations
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Journal ArticleDOI
Utility of a New Procedure for Diagnosing Mental Disorders in Primary Care: The PRIME-MD 1000 Study
Robert L. Spitzer,Janet B. W. Williams,Kurt Kroenke,Mark Linzer,Frank V. deGruy,Steven R. Hahn,David S. Brody,Jeffrey G. Johnson +7 more
TL;DR: Primary Care Evaluation of Mental Disorders appears to be a useful tool for identifying mental disorders in primary care practice and research.
Journal ArticleDOI
Diagnostic Interview for Genetic Studies: Rationale, Unique Features, and Training
John I. Nurnberger,Mary C. Blehar,Charles A. Kaufmann,Carolyn York-Cooler,Sylvia G. Simpson,Jill M. Harkavy-Friedman,Joanne B. Severe,Dolores Malaspina,Theodore Reich +8 more
TL;DR: The DIGS is designed to be employed by interviewers who exercise significant clinical judgment and who summarize information in narrative form as well as in ratings, and should be useful as part of archival data gathering for genetic studies of major affective disorders, schizophrenia, and related conditions.
Journal ArticleDOI
Psychosis prediction: 12-month follow up of a high-risk ("prodromal") group.
Alison R. Yung,Lisa J. Phillips,Hok Pan Yuen,Shona M. Francey,Colleen A. McFarlane,Mats Hallgren,Patrick D. McGorry,Patrick D. McGorry +7 more
TL;DR: It is illustrated that it is possible to recruit and follow up individuals at ultra high risk of developing psychosis within a relatively brief follow-up period and some highly significant predictors of psychosis were found.
Journal ArticleDOI
Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms.
Patrick D. McGorry,Alison R. Yung,Lisa J. Phillips,Hok Pan Yuen,Shona M. Francey,Elizabeth Cosgrave,Dominic Germano,Jenny Bravin,Tony McDonald,Alison Blair,Stephen Adlard,Henry J. Jackson +11 more
TL;DR: More specific pharmacotherapy and psychotherapy reduces the risk of early transition to psychosis in young people at ultra-high risk, although their relative contributions could not be determined.
Journal ArticleDOI
Assessment of insight in psychosis.
TL;DR: The Scale to Assess Unawareness of Mental Disorder has good reliability and validity and has certain advantages over previous measures of insight, suggesting the usefulness of a multidimensional view of this complex concept.
References
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TL;DR: A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
A practical method for grading the cognitive state of patients for the clinician
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A rating scale for depression
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Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Research diagnostic criteria: Rationale and reliability.
TL;DR: The development and initial reliability studies of a set of specific diagnostic criteria for a selected group of functional psychiatric disorders, the Research Diagnostic Criteria (RDC), indicate high reliability for diagnostic judgments made using these criteria.