Open AccessJournal Article
The disposition of caffeine during and after pregnancy.
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This article is published in Seminars in Perinatology.The article was published on 1981-10-01 and is currently open access. It has received 180 citations till now. The article focuses on the topics: Postpartum period & Pregnancy.read more
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Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use
TL;DR: Caffeine is the most widely consumed behaviorally active substance in the world and almost all caffeine comes from dietary sources (beverages and food).
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Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects.
TL;DR: Caffeine is the most widely consumed central-nervous-system stimulant as discussed by the authors, however, its psychostimulant action on man is often subtle and not very easy to detect.
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Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach.
TL;DR: Evaluating the pharmacokinetic data of a variety of drugs during pregnancy and using a mechanistic-based approach can start to predict the effect of pregnancy for a large number of clinically used drugs.
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Gender Effects in Pharmacokinetics and Pharmacodynamics
TL;DR: Female-specific issues such as pregnancy, menopause, oral contraceptive use and menstruation may also have profound effects on drug metabolism, and sex differences in drug metabolism may be involved in the higher incidence of adverse reactions to drugs in women compared with men.
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Are we dependent upon coffee and caffeine? A review on human and animal data.
TL;DR: It appears that although caffeine fulfils some of the criteria for drug dependence and shares with amphetamines and cocaine a certain specificity of action on the cerebral dopaminergic system, the methylxanthine does not act on the dopamine structures related to reward, motivation and addiction.