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Journal ArticleDOI

The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches

TLDR
The results of the present study indicate that changes in the hormonal concentrations affect the mechanism of abortion in different ways.
About
This article is published in Animal Reproduction Science.The article was published on 2014-05-01. It has received 10 citations till now. The article focuses on the topics: Aglepristone.

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Journal ArticleDOI

Aglepristone: A review on its clinical use in animals

Anne Gogny, +1 more
- 01 Mar 2016 - 
TL;DR: Treatment of feline fibroadenomatosis using aglepristone has given promising results, but repeat treatment may be necessary in cats previously treated with long-acting progestagens.
Journal ArticleDOI

Factors affecting the fate of the canine corpus luteum: Potential contributors to pregnancy and non-pregnancy

TL;DR: The one clinically most efficient mechanism of interrupting a pregnancy in the dog is to block P4 receptors using an antigestagen in the second half of diestrus, however, several luteotropic factors could be used to enhance the chances of pregnancy.
Journal ArticleDOI

Fertility outcome after medically treated pyometra in dogs.

TL;DR: It is concluded that medical treatment with aglepristone+cloprostenol is effective and safe, preserving subsequent fertility, as demonstrated by negligible changes in LS.
Journal ArticleDOI

Association of luteal blood flow with follicular size, serum estrogen and progesterone concentrations, and the inducibility of luteolysis by PGF2α in dairy cows.

TL;DR: A strong correlation was determined to exist between the results of the visual examination of the images and the results obtained for the LBF area with the use of the Pixel Flux software and the possibility of increase in serum estrogen and progesterone concentrations in parallel with increased luteal blood flow (LBF).
Journal ArticleDOI

Progesterone receptor blockers: historical perspective, mode of function and insights into clinical and scientific applications

TL;DR: Besides their clinical application, antigestagens are used in research for investigating P4-dependent physiological and pathological processes and do not require the presence of the natural ligand for their action.
References
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Journal ArticleDOI

Progesterone receptor blockage: Effect on uterine contractility and early pregnancy

M Bygdeman, +1 more
- 01 Jul 1985 - 
TL;DR: Withdrawal of progesterone locally by RU 486 treatment resulted in the development of a regular uterine activity which was in sharp contrast to the low level contractility pattern found in the untreated control patients.
Journal ArticleDOI

Temporal aspects of the regulation of corpus luteum function by luteinizing hormone, prolactin and placental luteotrophin during the first half of pregnancy in the rat.

TL;DR: Intact rats were injected once, subcutaneously, with either 1.0 mg of ergocornine, free base (ECO), to prevent prolactin release, or an equine antiserum to bovine LH (LH-AS), to neutralize endogenous LH, on one of the days between days 6 and 12 of pregnancy.
Journal Article

Ultrasonographic appearance of the uterus, placenta, fetus, and fetal membranes throughout accurately timed pregnancy in beagles.

TL;DR: Serial ultrasonographic examinations were performed on 8 Beagle bitches from 20 to 60 days pregnant to determine time of first detection, appearance, and sizes of selected features of pregnancy and head diameter was the most accurate for estimation of gestational age.
Journal ArticleDOI

Prostaglandin F2α induced luteolysis, hypothermia, and abortions in beagle bitches

TL;DR: Since PGF2alpha can induce complete luteolysis it may be of use as an abortifacient in the bitch and dependent on a fall in progesterone, radioimmunoassayed in samples collected before, during, and after a 72 hr treatment period for Beagle bitches.
Journal ArticleDOI

Regulation of corpus luteum-function in the bitch.

TL;DR: It is concluded that luteal regression as monitored by the gradual decrease of systemic progesterone concentrations in the dog is not an actively regulated but rather a permissive process.
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