The heterogeneity of Epithelioid Hemangioendothelioma (EHE): A case series and review of the literature with emphasis on treatment options.
Stijn Witte,Marije E. Weidema,Suzanne E. J. Kaal,Yvonne M.H. Versleijen-Jonkers,Uta Flucke,Winette T. A. van der Graaf,Ingrid M.E. Desar +6 more
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In this article, the authors present five cases of EHE emphasizing diversity in presentation, treatment, and prognosis, and present a review of the literature on EHE treatment options.About:
This article is published in Seminars in Oncology.The article was published on 2021-06-01 and is currently open access. It has received 6 citations till now. The article focuses on the topics: Epithelioid hemangioendothelioma.read more
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The oncogenic fusion protein TAZ-CAMTA1 promotes genomic instability and senescence through hypertranscription
TL;DR: In this paper , the authors developed a model system whereby TAZ-CAMTA1 expression is induced by doxycycline in primary endothelial cells, and they established that upon TAZ CAMTA 1 expression, the cells rapidly entered a hypertranscription state, triggering considerable DNA damage.
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Establishment and Validation of a Nomogram Prognostic Model for Epithelioid Hemangioendothelioma
TL;DR: The nomogram model may play an important role in predicting the survival rate for EHE patients, with good concordance and accuracy, and can be applied in clinical practice.
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Delayed metastatic pulmonary epithelioid hemangioendothelioma of the femoral vessels: case report and literature review
TL;DR: In this paper , a 40-year-old female presented with a painful right groin mass and swelling in the lower extremity, and a 3.8 cm soft tissue mass was identified in the femoral sheath with the abutment of femoral artery on a CT scan.
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Prognostic Factors in Epithelioid Hemangioendothelioma: Analysis of a Nationwide Molecularly/Immunohistochemically Confirmed Cohort of 57 Cases
Tess Tomassen,Yvonne M.H. Versleijen-Jonkers,Melissa H.S. Hillebrandt-Roeffen,Patricia van Cleef,Thijs van Dalen,Marije E. Weidema,Ingrid M.E. Desar,Uta Flucke,Joost van Gorp +8 more
TL;DR: In this paper , the authors investigated prognostic factors based on clinicopathologic findings in a molecularly/immunohistochemically confirmed nationwide multicenter cohort of 57 EHE cases, and the overall survival rate was 71.4% at 1 year and 50.7% at 5 years.
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Successful chemotherapy with continuous immunotherapy for primary pulmonary endovascular epithelioid hemangioendothelioma: A case report
TL;DR: In this article , a 42-year-old man with multiple mild metabolic uptakes in pulmonary endovascular filling defect with a maximum standardized uptake value of 4.5 by 18-fluorodeoxyglucose/fibroblast associated protein inhibitor-positron emission tomography/ computed tomography was reported.
References
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Journal ArticleDOI
Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial
Winette T. A. van der Graaf,Jean-Yves Blay,Sant P. Chawla,Dong Wan Kim,B. Bui-Nguyen,Paolo G. Casali,Patrick Schöffski,Massimo Aglietta,Arthur P. Staddon,Yasuo Beppu,Axel Le Cesne,Hans Gelderblom,Ian Judson,Nobuhito Araki,M. Ouali,Sandrine Marreaud,Rachel Hodge,Mohammed R. Dewji,Corneel Coens,George D. Demetri,Christopher D.M. Fletcher,Angelo Paolo Dei Tos,Peter Hohenberger +22 more
TL;DR: This phase 3 study investigated the effect of pazopanib on progression-free survival in patients with metastatic non-adipocytic soft-tissue sarcoma after failure of standard chemotherapy.
Journal ArticleDOI
Phase II Study of Sorafenib in Patients With Metastatic or Recurrent Sarcomas
Robert G. Maki,David R. D'Adamo,Mary L. Keohan,Michael Saulle,Scott M. Schuetze,Samir D. Undevia,Michael B. Livingston,Matthew M. Cooney,Martee L. Hensley,Monica M. Mita,Chris H. Takimoto,Andrew S. Kraft,Anthony D. Elias,Bruce Brockstein,Nathalie E. Blachere,Mark A. Edgar,Lawrence H. Schwartz,Li-Xuan Qin,Cristina R. Antonescu,Gary K. Schwartz +19 more
TL;DR: As a single agent, sorafenib has activity against angiosarcoma and minimal activity against other sarcomas, and statistical modeling in this limited patient cohort indicated sorafinib toxicity was correlated inversely to patient height.
Journal ArticleDOI
Epithelioid hemangioendothelioma of the liver: a clinicopathologic study of 137 cases.
TL;DR: Epithelioid hemangioendothelioma is a rare neoplasm of vascular origin that occurs in the liver and other organs; its etiology is unknown.
Journal ArticleDOI
Primary malignant hepatic epithelioid hemangioendothelioma: a comprehensive review of the literature with emphasis on the surgical therapy.
Arianeb Mehrabi,Arash Kashfi,Hamidreza Fonouni,Peter Schemmer,Bruno M. Schmied,Peter Hallscheidt,Peter Schirmacher,Jürgen Weitz,Helmut Friess,Markus W. Büchler,Jan Schmidt +10 more
TL;DR: A comprehensive review of the literature on HEH is presented, with a focus on clinical outcome after different therapeutic strategies, to suggest LTx is an acceptable option for patients who have HEH with extrahepatic manifestation.
Journal ArticleDOI
Sarcoma classification: an update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone.
TL;DR: Changes in the classification of soft tissue and bone sarcomas as well as tumors of intermediate biologic potential in the 2013 World Health Organization volume are reviewed, new molecular insights into these tumors, and associated surgical and clinical implications are reviewed.