Open AccessJournal Article
THE INFLUENCES OF CHITOSAN FROM Penaeus monodon ON C-REACTIVE PROTEIN EXPRESSION IN AORTA AND CORONARY ARTERY OF SPRAGUE DAWLEY RATS BY HIGH FAT INDUCTION
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TLDR
Chitosan was able to prevent atheroma plaque formation in coronary artery and CRP may involve in atherosclerosis.Abstract:
The objective of this study was to analyze the influences of chitosan on C-Reactive Protein expression in
aorta and coronary artery of Sprague Dawley rats by high fat induction. The animals for this study were 20
adult male rats divided into four groups, i.e. group I as the control was fed with basal diet containing normal
fat for 3 months, group II was fed diet containing high fat for 3 months, group III was fed diet containing
high fat and given chitosan 180 mg per kg body weight per day orally in 2 ml aquadest for 3 months, group
IV was fed diet containing high fat for 3 months and after 1 month given chitosan 180 mg per kg body weight
per day orally in 2 ml aquadest for 2 months. Each group consisted of five animals. After 90 days, the rats
were necropsied and the hearts were collected to histopathological and immunohistochemical analysis by
immunohistochemistry streptavidin-biotin method. C-Reactive Protein expression in aorta was negative.
Chitosan was able to prevent atheroma plaque formation in coronary artery and CRP may involve in
atherosclerosisread more
Citations
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KADAR APOPROTEIN A DAN APOPROTEIN B SERUM DARAH TIKUS PUTIH Sprague Dawley HIPERLIPIDEMIA SETELAH DIBERI CANGKANG UDANG LAUT (Penaeus monodon F.)
TL;DR: The result showed that high fat diet increased apoprotein B level, sea shrimp carapace increased of apop protein A level and decreased of apop Protein B level.
References
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Atherosclerosis — An Inflammatory Disease
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C-reactive protein: a critical update
TL;DR: Information is provided about CRP as a protein and an acute-phase reactant, and a knowledge-based framework for interpretation and analysis of clinical observations of CRP in relation to cardiovascular and other diseases, that identifies it as a possible therapeutic target.
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TL;DR: In this paper, analytical methods and fractionation techniques of dietary fibres are evaluated for improving physical and structural properties of hydration, oil holding capacity, viscosity, texture, sensory characteristics, and shelf-life.