Journal ArticleDOI
The production of mucosal ulceration in the rabbit gut by intra‐arterial injection of microspheres
I. Aaronson,C. L. Berry +1 more
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This article is published in The Journal of Pathology.The article was published on 1970-11-01. It has received 85 citations till now.read more
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Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts
TL;DR: Direct biochemical evidence is provided that diploid strains from AT donors are indeed impaired in DNA repair; in particular, these cell lines possess an enzymatic defect in an excision-type repair process operating on γ-modified nitrogenous base residues.
Journal ArticleDOI
Cleavage of pyrimidine dimers in specific DNA sequences by a pyrimidine dimer DNA-glycosylase of M. luteus
William A. Haseltine,Lynn K. Gordon,Christina P. Lindan,Robert H. Grafstrom,Nancy L. Shaper,Lawrence Grossman +5 more
TL;DR: It is proposed that strand scission at a dimer site by the M. luteus enzyme requires two activities, a pyrimidine dimer DNA-glycosylase and an apyrimidinic/apurinic endonuclease.
Journal ArticleDOI
Photoreactivation of Escherichia coli after Low- or Medium-Pressure UV Disinfection Determined by an Endonuclease Sensitive Site Assay
TL;DR: It was found that inactivating light at a broad range of wavelengths effectively reduced subsequent photoreactivation, which could be an advantage that MP UV irradiation has over conventional LPUV irradiation.
Journal ArticleDOI
Determination of pyrimidine dimers in Escherichia coli and Cryptosporidium parvum during UV light inactivation, photoreactivation, and dark repair.
Kumiko Oguma,Hiroyuki Katayama,Hiroshi Mitani,Shigemitsu Morita,Tsuyoshi Hirata,Shinichiro Ohgaki +5 more
TL;DR: The infectivity of C. parvum was suggested to not recover either by photoreactivation or by dark repair even after the repair of pyrimidine dimers in the genomic DNA, indicating that the ESS assay is comparable to the method conventionally used to measure colony-forming ability.
Journal ArticleDOI
UV-induced DNA damage initiates release of MMP-1 in human skin.
Kelly Dong,Niusha Damaghi,Stephanie D. Picart,Nelli G. Markova,Kei Obayashi,Yuri Okano,Hitoshi Masaki,Susanne Grether-Beck,Jean Krutmann,Kenneth A. Smiles,Daniel B. Yarosh +10 more
TL;DR: UV damage to keratinocytes of the epidermis may participate in the destruction of collagen in the dermis by release of soluble mediators that signal fibroblasts to release MMP‐1, a hallmark of photoaging.
References
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Journal ArticleDOI
Experimental study of devascularization of the colon.
TL;DR: A number of standardized controlled vascular occlusions are produced in the experimental animal and studied to study their general and local effects in the hope of increasing the knowledge of what may be expected in the clinical situation.
Journal ArticleDOI
Mortality in neonatal Hirschsprung's disease: With particular reference to enterocolitis
Graham C. Fraser,Colin Berry +1 more
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The experimental production of colitis in the rabbit with particular reference to Hirschsprung's disease
C.L. Berry,G.C. Fraser +1 more
TL;DR: An experimental model of mucosal necrosis of the type seen in enterocolitis has been produced in the rabbit by local and systemic injection of endotoxin and the relevance of this model to enteringocolitis in Hirschsprung's disease is discussed.