Journal ArticleDOI
The synthesis of fused ring nitrogen heterocycles via regiospecific intramolecular heck reactions
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In this article, a series of palladium cyclizations of aryl iodides and vinyl bromides onto proximate alkenes or heteroaromatic rings (indole, pyrrole) lead to a wide variety of fused ring systems.About:
This article is published in Tetrahedron.The article was published on 1990-01-01. It has received 123 citations till now. The article focuses on the topics: Ring (chemistry) & Palladium(II) acetate.read more
Citations
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Aryl-aryl bond formation by transition-metal-catalyzed direct arylation.
TL;DR: A number of improvements have developed the former process into an industrially very useful and attractive method for the construction of aryl -aryl bonds, but the need still exists for more efficient routes whereby the same outcome is accomplished, but with reduced waste and in fewer steps.
Journal ArticleDOI
Direct transition metal-catalyzed functionalization of heteroaromatic compounds
TL;DR: This critical review summarizes the progress made in this field until November 2006 and describes the development of C-H activation methods for direct functionalization of heterocyclic molecules.
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Synthesis of heterocycles via palladium-catalyzed oxidative addition.
Gilson Zeni,Richard C. Larock +1 more
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Cyclic carbopalladation. a versatile synthetic methodology for the construction of cyclic organic compounds
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Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds
TL;DR: Conditions for the palladium-catalyzed direct arylation of a wide range of heterocycles with aryl bromides are reported and employ a stoichiometric ratio of both coupling partners, as well as a substoichiometric quantity of pivalic acid, which results in significantly faster reactions.
References
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Journal ArticleDOI
The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)]
TL;DR: The cross-coupling of organotin reagents with a variety of organic electrophiles, catalyzed by palladium, provides a novel method for generating a carbon-carbon bond.
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Intramolecular alkene arylations for rapid assembly of polycyclic systems containing quaternary centers. A new synthesis of spirooxindoles and other fused and bridged ring systems
TL;DR: Exemples d'arylations intramoleculculeries d'arenes halogenes o-substitues par un groupe insature are given in this article.
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Mechanism of arylation and carbomethoxylation of olefins with organopalladium compounds
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1,2-Additions to heteroatom-substituted olefins by organopalladium reagents
G. Doyle Daves,Anders Hallberg +1 more
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Catalytic asymmetric carbon-carbon bond formation: asymmetric synthesis of cis-decalin derivatives by palladium-catalyzed cyclization of prochiral alkenyl iodides
TL;DR: Une synthese asymetrique catalytique utilisant la reaction de type Heck a ete realisee pour la premiere fois, donnant un des derives de cis-decaline avec plus de 46% d'exces enantiomere.
Related Papers (5)
Intramolecular alkene arylations for rapid assembly of polycyclic systems containing quaternary centers. A new synthesis of spirooxindoles and other fused and bridged ring systems
Aryl-aryl bond formation by transition-metal-catalyzed direct arylation.
Palladium-catalysed cyclisation of 2-substituted halogenoarenes by dehydrohalogenation
D.E. Ames,A. Opalko +1 more