Journal ArticleDOI
Towards the laser photochemistry of the cornea : studies of the most common and highly absorbing aliphatic amino acids in collagen
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In this paper, the photochemical properties of various aliphatic amino acid residues common in collagen (Gly, Pro, Ala and Hyp), those with high absorption (Arg, Lys and His) and some others, as well as two dipeptides have been studied in neutral aqueous solution using 193 nm excimer laser irradiation.Abstract:
The photochemical properties of various aliphatic amino acid residues common in collagen (Gly, Pro, Ala and Hyp), those with high absorption (Arg, Lys and His) and some others, as well as two dipeptides (Gly-Pro and Pro-Gly) have been studied in neutral aqueous solution using 193 nm excimer laser irradiation The quantum yields for decomposition and electron ejection (002–020) are determined and the relative probability of photochemical damage of specific residues estimated The peptide bond is likely to be the main target in collagen Its scission could be the most important photochemical reaction taking place at 193 nm laser irradiation of the cornearead more
Citations
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Wavelength dependence of femtosecond laser-induced breakdown in water and implications for laser surgery
TL;DR: In this article, the authors measured the bubble threshold from ultraviolet to near-infrared wavelengths and found a continuous decrease of the irradiance threshold with increasing wavelength, which is of interest for parameter selection in laser surgery.
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Surface foaming of collagen, chitosan and other biopolymer films by KrF excimer laser ablation in the photomechanical regime
TL;DR: In this article, a 3D polymer micro-foam with interconnected pores was obtained from rat tail tendons, which was exposed to single pulses of radiation of the KrF laser with increasing fluence.
Journal ArticleDOI
Laser-induced photodecomposition of amino acids and peptides: extrapolation to corneal collagen
TL;DR: In this article, the laser photochemistry of aromatic and aliphatic amino acids and small peptides in neutral aqueous solution is described. And the relative probabilities of photochemical damage of specific residues are estimated.
Journal ArticleDOI
Matrix-controlled photofragmentation of formamide: dynamics simulation in argon by nonadiabatic QM/MM method
Mirjana Eckert-Maksić,Mario Vazdar,Matthias Ruckenbauer,Mario Barbatti,Thomas Müller,Hans Lischka +5 more
TL;DR: The short-time photodynamics of formamide embedded into an Ar matrix starting from the low-lying singlet excited S(1) (n(0)π*) and S(2) (ππ*) states were explored using a nonadiabatic photodynamics QM/MM approach and it is shown that embedding of the formamide molecule in the argon matrix has strong impact on the outcome of the process.
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Thermal stability of UV-irradiated collagen in bovine lens capsules and in bovine cornea.
TL;DR: DSC suggested that collagen was reduced by UV to different polypeptides of different molecular weight and different lower thermal stabilities, which suggested an increase of intermolecular cross-linking.
References
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Book
Textbook of Biochemistry With Clinical Correlations
TL;DR: Textbook of biochemistry: with clinical correlations, Textbook of bioinformatics: withclinical correlations, and more.
Journal ArticleDOI
Excimer Laser Surgery of the Cornea
TL;DR: Applying the far-ultraviolet light in short intense pulses permitted us to control the depth of the incision with great precision and it was found that 1 joule/cm2 ablates corneal tissue to a depth of 1 micron.
Journal ArticleDOI
Excimer laser ablation of the cornea and lens. Experimental studies.
Carmen A. Puliafito,Roger F. Steinert,Thomas F. Deutsch,Franz Hillenkamp,Ellen J. Dehm,Catherine M. Adler +5 more
TL;DR: The pulsed ultraviolet excimer laser has been used to produce tissue ablation with a high degree of precision and with minimal thermal damage to adjacent structures, and threshold fluence for corneal and lens ablation was higher at 248 nm than at 193 nm.
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An Ultrastructural Study of Corneal Incisions Induced by an Excimer Laser at 193 nm
TL;DR: Far ultraviolet light (193 nm) produced by an excimer laser has been used to produce a variety of incisions in the corneas of anaesthetised rabbits but tissue was lost from the site of irradiation but the nature of the underlying molecular interactions responsible for such tissue erosion remain obscure.
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Long-term Healing of the Central Cornea after Photorefractive Keratectomy Using an Excimer Laser
TL;DR: Using an excimer laser at 193 nm, 3-mm diameter discs were ablated from the optical zone of monkey corneas at a variety of depths up to 130 micron and showed a normal morphology in this layer with the exception that basal cells were slightly more elevated particularly at the disc margins where the epithelium contained more cell layers.