Journal ArticleDOI
Transcription by RNA Polymerase III
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This article is published in Annual Review of Biochemistry.The article was published on 1988-01-01. It has received 565 citations till now. The article focuses on the topics: RNA polymerase II & Transcription factor II D.read more
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A three-hybrid system to detect RNA-protein interactions in vivo
Dhruba J. Sengupta,Beilin Zhang,Brian C. Kraemer,Pascale Pochart,Stanley Fields,Marvin Wickens +5 more
TL;DR: A yeast genetic method to detect and analyze RNA-protein interactions in which the binding of a bifunctional RNA to each of two hybrid proteins activates transcription of a reporter gene in vivo, which enables the rapid, phenotypic detection of specific RNA- protein interactions.
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The expanding RNA polymerase III transcriptome.
TL;DR: The role of RNA polymerase (Pol) III in eukaryotic transcription is commonly thought of as being restricted to a small set of highly expressed, housekeeping non-protein-coding (nc)RNA genes, but recent studies have remarkably expanded the set of known Pol III-synthesized ncRNAs, suggesting that gene-specific Pol III regulation is more common than previously appreciated.
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Basic Mechanisms of Transcript Elongation and Its Regulation
TL;DR: New models for the structure of ternary complexes, and for the mechanism by which they move along DNA, provide plausible explanations for novel biochemical reactions that have been observed and offer the prospect of understanding many significant biological regulatory systems at the molecular level.
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S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors
TL;DR: It is shown here that TFIIIB alone correctly positions pol III for repeated cycles of transcription on both genes, with the same efficiency as fully assembled transcription complexes.
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Functional evidence for an RNA template in telomerase.
TL;DR: Functional analysis showed that the sequence 5' CAAAACCCCAAA 3' in this RNA is the template for synthesis of telomeric TTTTGGGG repeats by the Euplotes telomerase, and Telomerase can now be defined as a specialized reverse transcriptase.