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Open AccessJournal ArticleDOI

Ultrasound elastography: Principles and techniques

TLDR
The principles of elastographic techniques are introduced and a technical summary for the main elastography techniques are given: from quasi-static methods that require a static compression of the tissue to dynamic methods that uses the propagation of mechanical waves in the body.
Abstract
Ultrasonography has been widely used for diagnosis since it was first introduced in clinical practice in the 1970's. Since then, new ultrasound modalities have been developed, such as Doppler imaging, which provides new information for diagnosis. Elastography was developed in the 1990's to map tissue stiffness, and reproduces/replaces the palpation performed by clinicians. In this paper, we introduce the principles of elastography and give a technical summary for the main elastography techniques: from quasi-static methods that require a static compression of the tissue to dynamic methods that uses the propagation of mechanical waves in the body. Several dynamic methods are discussed: vibro-acoustography, Acoustic Radiation Force Impulsion (ARFI), transient elastography, shear wave imaging, etc. This paper aims to help the reader at understanding the differences between the different methods of this promising imaging modality that may become a significant tool in medical imaging.

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Citations
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Journal ArticleDOI

Ultrasound Elastography: Review of Techniques and Clinical Applications

TL;DR: While ultrasound elastography has shown promising results for non-invasive assessment of liver fibrosis, new applications in breast, thyroid, prostate, kidney and lymph node imaging are emerging.
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Ultrasonic Neuromodulation Causes Widespread Cortical Activation via an Indirect Auditory Mechanism

TL;DR: Surprisingly, cortical activity patterns are found consistent with indirect activation of auditory pathways rather than direct neuromodulation at the ultrasound focus, revealing an indirect auditory mechanism for ultrasound-induced cortical activity and movement.
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Non-invasive diagnosis of liver fibrosis and cirrhosis

TL;DR: The authors may be witnessing in recent years the beginning of the end of the first phase for the development of non-invasive markers, and early evidence suggests that they might be at least as good as liver biopsy.
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Elastography for Muscle Biomechanics: Toward the Estimation of Individual Muscle Force.

TL;DR: This review presents a series of experiments that used ultrasound shear wave elastography to support the hypothesis that muscle stiffness is linearly related to both active and passive muscle forces.
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Transient elastography (FibroScan(®)) with controlled attenuation parameter in the assessment of liver steatosis and fibrosis in patients with nonalcoholic fatty liver disease - Where do we stand?

TL;DR: In this article, transient elastography (FibroScan® TE) with controlled attenuation parameter (CAP) has demonstrated good accuracy in quantifying the levels of liver steatosis and fibrosis in patients with NAFLD.
References
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Journal ArticleDOI

Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues

TL;DR: Initial results of several phantom and excised animal tissue experiments are reported which demonstrate the ability of this technique to quantitatively image strain and elastic modulus distributions with good resolution, sensitivity and with diminished speckle.
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Transient elastography: a new noninvasive method for assessment of hepatic fibrosis

TL;DR: Liver elasticity measurements were reproducible, operator-independent and well correlated and the intra- and interoperator reproducibility of the technique, as well as its ability to quantify liver fibrosis, were evaluated in 106 patients with chronic hepatitis C.
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Prospective Comparison of Transient Elastography, Fibrotest, APRI, and Liver Biopsy for the Assessment of Fibrosis in Chronic Hepatitis C

TL;DR: FibroScan is a simple and effective method for assessing liver fibrosis, with similar performance to FibroTest and APRI, and could avoid a biopsy procedure in most patients with chronic hepatitis C.
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Supersonic shear imaging: a new technique for soft tissue elasticity mapping

TL;DR: The first in vivo investigations made on healthy volunteers emphasize the potential clinical applicability of SSI for breast cancer detection and results validating SSI in heterogeneous phantoms are presented.
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Shear wave elasticity imaging: a new ultrasonic technology of medical diagnostics

TL;DR: A physical and mathematical basis of SWEI is presented and some experimental results of pilot studies proving feasibility of this new ultrasonic technology are presented, including a theoretical model of shear oscillations in soft biological tissue remotely induced by the radiation force of focused ultrasound.
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