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Open AccessJournal ArticleDOI

Ultrasound in the diagnosis of peripheral neuropathy: structure meets function in the neuromuscular clinic

TLDR
Closer scrutiny of nerve abnormalities beyond assessment of nerve calibre may allow for more accurate diagnostic classification of PN, as well as contribute to the understanding of the intersection of structure and function in PN.
Abstract
Peripheral nerve ultrasound (US) has emerged as a promising technique for the diagnosis of peripheral nerve disorders. While most experience with US has been reported in the context of nerve entrapment syndromes, the role of US in the diagnosis of peripheral neuropathy (PN) has recently been explored. Distinctive US findings have been reported in patients with hereditary, immune-mediated, infectious and axonal PN; US may add complementary information to neurophysiological studies in the diagnostic work-up of PN. This review describes the characteristic US findings in PN reported to date and a classification of abnormal nerve US patterns in PN is proposed. Closer scrutiny of nerve abnormalities beyond assessment of nerve calibre may allow for more accurate diagnostic classification of PN, as well as contribute to the understanding of the intersection of structure and function in PN.

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Journal ArticleDOI

New technologies for the assessment of neuropathies

TL;DR: These new and emerging techniques and their effects on diagnosis, treatment strategies and prognosis in a variety of peripheral neuropathies, including entrapments, brachial plexopathies, immune and inherited neuro Pathies, and small-fibre neuropathie are reviewed.
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Differentiating lower motor neuron syndromes.

TL;DR: The spectrum of LMN syndromes that may develop in adulthood is outlined to provide a framework for the clinician assessing a patient presenting with predominantly LMN features and to recognise, as effective treatments are available.
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Ultrasound and electrophysiologic findings in patients with Guillain–Barré syndrome at disease onset and over a period of six months

TL;DR: Ulasonographic detection of cervical spinal nerve enlargement supports the diagnosis of GBS in the early phase and its regression may be a good parameter for the clinical restitution over time.
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Advances in the neurological and neurosurgical management of peripheral nerve trauma

TL;DR: Advances in non-invasive imaging techniques to diagnose and monitor nerve injury and regeneration are being developed, and have the potential to streamline the decision-making process and provide more effective ways to maximise functional outcomes following severe peripheral nerve trauma.
Journal ArticleDOI

Ultrasound elastography for the evaluation of peripheral nerves: A systematic review.

TL;DR: The aim of this systematic review is to summarize the current literature on the use of ultrasound elastography in the evaluation of peripheral neuropathy, and to raise prospects for future clinical and research applications.
References
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Journal Article

Chronic inflammatory polyradiculoneuropathy.

TL;DR: The diagnostic criteria, natural history, nerve conduction characteristics, pathology, laboratory features, and efficacy of corticosteroid treatment have been evaluated personally in 53 patients with chronic inflammatory polyradiculoneuropathy who were followed up for an average of about 7.5 years.
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The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK

TL;DR: This is the first study of the incidence and lifetime prevalence of neurological disorders in recent times and it is found that these disorders give rise to significant morbidity in the community.
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Chemotherapy-induced peripheral neurotoxicity: a critical analysis.

TL;DR: This review will address the increasing importance and challenge of chemotherapy‐induced neurotoxicity, with a focus on neuropathy associated with the treatment of breast cancer, colorectal cancer, testicular cancer, and hematological cancers.
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Epidemiology of peripheral neuropathy.

TL;DR: The commoner forms of peripheral neuropathy, single and multiple mononeuropathy, and radiculopathy are considered separately because they may be rather commoner than is usually thought.
Journal ArticleDOI

Multifocal demyelinating neuropathy with persistent conduction block

TL;DR: Four patients with a chronic asymmetric sensorimotor neuropathy most pronounced in the upper extremities with focal involvement of individual nerves had acute optic neuritis, indicating that the disorder was not always restricted to the peripheral nervous system.
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