Journal ArticleDOI
Vaginal fluid urea and creatinine in diagnosis of premature rupture of membranes
Hasan Kafali,Cevdet Oksuzler +1 more
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TLDR
Vaginal washing fluid urea and creatinine determination for the diagnosis of PROM is a reliable, simple and rapid test.Abstract:
Objective:
To evaluate the reliability of vaginal fluid urea and creatinine for the diagnosis of premature rupture of membranes (PROMs).read more
Citations
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Journal Article
Contemporary Diagnosis and Management of Preterm Premature Rupture of Membranes
TL;DR: Management options include admission to hospital, amniocentesis to exclude intra-amniotic infection, and administration of antenatal corticosteroids and broad-spectrum antibiotics, if indicated.
Journal ArticleDOI
Diagnosis of Premature Rupture of Membranes: Inspiration From the Past and Insights for the Future
Amira El-Messidi,Alan Cameron +1 more
TL;DR: The subjectivity and poor sensitivity of early diagnostic techniques for confirmation of ruptured membranes sparked technical advancements using biochemical markers, but none of these biochemical tests have gained popularity and novel techniques involving placental markers such as placental alpha microglobulin-1 may provide a future solution to the problem of diagnosing chorioamniotic membrane rupture.
Journal ArticleDOI
Use of cervicovaginal fluid for the identification of biomarkers for pathologies of the female genital tract
TL;DR: The use of proteomic technology for analysis of human cervicovaginal fluid samples is promising and may lead to the discovery of new biomarkers which can improve disease prevention and therapy development.
Journal ArticleDOI
Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings
TL;DR: Both commercially available diagnostics and technologies that are currently in development to detect the leading causes of maternal and neonatal mortality are reviewed, highlighting key gaps in development where innovative design could increase access to technology and enable rapid diagnosis at the bedside.
Journal ArticleDOI
Placental α-microglobulin-1 to detect uncertain rupture of membranes in a European cohort of pregnancies
TL;DR: AT was more sensitive compared to clinical assessment, independent of the examiners experience and gestational age, and seems to be a cost-effective approach in the assessment of these patients with uncertain ROM.
References
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Journal Article
Fetal fibronectin: a method for detecting the presence of amniotic fluid.
Nancy L. Eriksen,Valerie M. Parisi,Susan Daoust,Bruce L. Flamm,Thomas J. Garite,Susan M. Cox +5 more
TL;DR: Fetal fibronectin is a sensitive test for detection of AF in the vagina and compares favorably to standard tests, and its low specificity suggests that the assay may detect an alteration in membrane integrity.
Journal ArticleDOI
Diagnosis of premature rupture of membranes by identification of β-HCG in vaginal washing fluid
TL;DR: Vaginal washing fluid beta-HCG determination for the diagnosis of PROM is reliable, simple and rapid test and a cut-off value is determined.
Journal ArticleDOI
Preterm premature rupture of the membranes: diagnosis and management
TL;DR: A gestational age-based approach to the management of the stable patient with preterm PROM offers the potential to reduce perinatal infectious and gestations age-dependent morbidity for patients who are amenable to conservative management.
Journal ArticleDOI
Comparative study of three vaginal markers of the premature rupture of membranes. Insulin like growth factor binding protein 1 diamine-oxidase pH.
Pascal Gaucherand,Bruno Salle,Philippe Sergeant,Suzanne Guibaud,Jocelyne Brun,Charles Albert Bizollon,René-Charles Rudigoz +6 more
TL;DR: Assessment of the diagnostic value of three vaginal markers ‐ insulin‐like growth factor binding protein 1, diamine‐oxidase and pH ‐ for diagnosis of the premature rupture of membranes.
Journal ArticleDOI
Vaginal fluid β-human chorionic gonadotropin level in the diagnosis of premature rupture of membranes
TL;DR: The measurement of β‐human chorionic gonadotropin (β‐HCG) level in the vaginal washing fluid could be useful for the diagnosis of premature rupture of membranes.