Value of Cardiovascular Magnetic Resonance Imaging–Derived Baseline Left Ventricular Ejection Fraction and Volumes for Precise Risk Stratification of Patients With Ischemic Cardiomyopathy: Insights From the Surgical Treatment for Ischemic Heart Failure (STICH) Trial
Ramdas G. Pai,Padmini Varadarajan,Jean L. Rouleau,Amanda Stebbins,Eric J. Velazquez,Hussein R. Al-Khalidi,Gerald M. Pohost +6 more
TLDR
The hypothesis that CMR-derived LVEF and volumes would provide improved risk stratification would be tested in the Surgical Treatment for Ischemic Heart Failure Trial population.Abstract:
Value of Cardiovascular Magnetic Resonance Imaging–Derived Baseline Left Ventricular Ejection Fraction and Volumes for Precise Risk Stratification of Patients With Ischemic Cardiomyopathy: Insights From the Surgical Treatment for Ischemic Heart Failure (STICH) Trial Ischemic cardiomyopathy accounts for approximately 50% of patients with heart failure and one-third of the patients undergoing coronary artery bypass surgery.1 Left ventricular (LV) ejection fraction (EF) and end-systolic volume index (ESVI) are predictors of mortality in these patients. Cardiovascular magnetic resonance (CMR) imaging can provide precise estimates of LV volumes and function. In the Surgical Treatment for Ischemic Heart Failure (STICH) Trial population,2 we tested the hypothesis that CMR-derived LVEF and volumes would provide improved risk stratification.read more
Citations
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Journal ArticleDOI
Surgical Treatment for Ischemic Heart Failure (STICH) trial: A review of outcomes.
TL;DR: The purpose of this comprehensive review is to outline the published data from the STICH trial and its substudies while providing a balanced assessment of the evidence‐based conclusions and criticisms that have followed.
Journal ArticleDOI
CD14, CD163, and CCR1 are involved in heart and blood communication in ischemic cardiac diseases.
TL;DR: Three hub genes, CD14, CD163, and CCR1, were identified and their involvement in the immune response and in the inflammatory response, which are the critical biochemical processes in ischemic HF, demonstrated that a special model may exist to help predict the mRNA level in the heart based on that in blood.
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Outcomes of Coronary Artery Bypass Grafting in Patients With Poor Myocardial Viability: A Systematic Review and Meta-Analysis of the Last Decade.
TL;DR: In this article , the authors assess whether the presence of myocardial viability is a predictor of mortality among patients undergoing coronary artery bypass grafting (CABG) through a systematic review meta-analysis.
Journal ArticleDOI
Left ventricular volume change and long-term outcomes in ischaemic cardiomyopathy with or without surgical revascularisation: A post-hoc analysis of a randomised controlled trial
Zhuo-Ming Zhou,Xiaodong Zhuang,Menghui Liu,B. Jian,Guangguo Fu,Xinxue Liao,Zhongkai Wu,Mengya Liang +7 more
TL;DR: In this paper , the authors performed a post-hoc analysis of the Surgical Treatment of Ischaemic Heart Failure (STICH) trial to investigate whether the association between post-therapeutic left ventricular volume change and long-term outcomes in ischaemic cardiomyopathy is influenced by the performance of coronary artery bypass grafting.
References
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Journal ArticleDOI
ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure): Developed in Collaboration With the International Society for Heart and Lung Transplantation; Endorsed by the Heart Failure Society of America.
Sharon A. Hunt,David W. Baker,Marshall H. Chin,Michael P. Cinquegrani,Arthur M. Feldman,Gary S. Francis,Theodore G. Ganiats,Sidney Goldstein,Gabriel Gregoratos,Mariell Jessup,R.Joseph Noble,Milton Packer,Marc A. Silver,Lynne W. Stevenson,Raymond J. Gibbons,Elliott M. Antman,Joseph S. Alpert,David P. Faxon,Valentin Fuster,Alice K. Jacobs,Loren F. Hiratzka,Richard O. Russell,Sidney C. Smith +22 more
TL;DR: In the United States, nearly 5 million patients in this country have heart failure, and nearly 500,000 patients are diagnosed with heart failure for the first time each year as mentioned in this paper.
Journal ArticleDOI
Coronary-Artery Bypass Surgery in Patients with Left Ventricular Dysfunction
Eric J. Velazquez,Kerry L. Lee,Marek A. Deja,Anil Jain,George Sopko,Andrey Marchenko,Imtiaz S. Ali,Gerald M. Pohost,Sinisa Gradinac,William T. Abraham,Michael Yii,Dorairaj Prabhakaran,Hanna Szwed,Paolo Ferrazzi,Mark C. Petrie,Pradit Panchavinnin,Robert O. Bonow,Gena Rankin,Robert H. Jones,Jean-Lucien Rouleau +19 more
TL;DR: In this randomized trial, patients assigned to CABG, as compared with those assigned to medical therapy alone, had lower rates of death from cardiovascular causes and ofdeath from any cause or hospitalization for cardiovascular causes.
Journal ArticleDOI
Coronary Bypass Surgery with or without Surgical Ventricular Reconstruction
Robert H. Jones,Eric J. Velazquez,Robert E. Michler,George Sopko,Jae K. Oh,Christopher M. O'Connor,James A. Hill,Lorenzo Menicanti,Zygmunt Sadowski,Patrice Desvigne-Nickens,Jean L. Rouleau,Kerry L. Lee +11 more
TL;DR: Adding surgical ventricular reconstruction to CABG reduced the left ventricular volume, as compared with CABGs alone, however, this anatomical change was not associated with a greater improvement in symptoms or exercise tolerance or with a reduction in the rate of death or hospitalization for cardiac causes.
Journal ArticleDOI
The Rationale and Design of the Surgical Treatment for IsChemic Heart failure (STICH) Trial
Eric J. Velazquez,Eric J. Velazquez,Kerry L. Lee,Kerry L. Lee,Christopher M. O'Connor,Christopher M. O'Connor,Jae K. Oh,Robert O. Bonow,Gerald M. Pohost,Arthur M. Feldman,Daniel B. Mark,Daniel B. Mark,Julio A. Panza,George Sopko,Jean L. Rouleau,Robert H. Jones,Robert H. Jones +16 more
TL;DR: The Surgical Treatment for Ischemic Heart Failure trial is a National Heart, Lung, and Blood Institute-funded multicenter international randomized trial addressing 2 specific primary hypotheses: coronary artery bypass grafting with intensive medical therapy improves long-term survival compared with survival with medical therapy alone.
Journal ArticleDOI
Relations between heart failure, ejection fraction, arrhythmia suppression and mortality: Analysis of the Cardiac Arrhythmia Suppression Trial
Al Hallstrom,Craig M. Pratt,H. L. Greene,H. L. Greene,M Huther,M Huther,Stephen S. Gottlieb,Stephen S. Gottlieb,Anthony N. DeMaria,Anthony N. DeMaria,J B Young,J B Young +11 more
TL;DR: Although heart failure as a prognostic feature appears to be somewhat superior to ejection fraction, both are powerful predictors of arrhythmia suppression and cardiac events in patients with ventricular arrhythmias after myocardial infarction.