Variable dosage compensation is associated with female consequences of an X-linked, male-beneficial mutation.
Jack G. Rayner,Thomas J. Hitchcock,Nathan W. Bailey +2 more
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In this article, it was suggested that dosage compensation mediates sexual antagonism over X-linked genes, based on the assumption that dose compensation scales phenotypic effects between genes.Abstract:
Recent theory has suggested that dosage compensation mediates sexual antagonism over X-linked genes. This process relies on the assumption that dosage compensation scales phenotypic effects between...read more
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Dissecting cricket genomes for the advancement of entomology and entomophagy
TL;DR: In this article , the progress of genomics of crickets is summarized and how the cricket genome can be beneficial to the food industry and how basic research based on cricket genome information can contribute to tackling global food security.
Journal ArticleDOI
Dissecting cricket genomes for the advancement of entomology and entomophagy
TL;DR: In this paper , the progress of genomics of crickets is summarized and how the cricket genome can be beneficial to the food industry and how basic research based on cricket genome information can contribute to tackling global food security.
Journal ArticleDOI
X chromosomes show relaxed selection and complete somatic dosage compensation across <i>Timema</i> stick insect species
Hailong Zhang,Tao Wang +1 more
TL;DR: In this paper , the authors used whole-genome sequencing to identify and characterize the evolution of the X chromosome in five species of Timema stick insects with XX:X0 sex determination.
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The diverse effects of phenotypic dominance on hybrid fitness
TL;DR: The results show that dominance could play an important role in the outcomes of hybridisation after secondary contact, and thus to the maintenance or collapse of isolating barriers, and suggest that simple additive models may still give good predictions for later-generation recombinant hybrids, even when dominance qualitatively alters outcomes for the F1.
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How much does the unguarded X contribute to sex differences in life span?
TL;DR: In this article , the authors used a simple population genetic model to show that the unguarded X effect on sex differential mortality is a function of several reasonably well-studied evolutionary parameters, including the proportion of the genome that is sex linked, the genomic deleterious mutation rate, the mean dominance of deleTERious mutations, the relative rates of mutation and strengths of selection in each sex, and the average effect of mutations on survival and longevity relative to their effects on fitness.
References
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edgeR: a Bioconductor package for differential expression analysis of digital gene expression data.
TL;DR: EdgeR as mentioned in this paper is a Bioconductor software package for examining differential expression of replicated count data, which uses an overdispersed Poisson model to account for both biological and technical variability and empirical Bayes methods are used to moderate the degree of overdispersion across transcripts, improving the reliability of inference.
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Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
TL;DR: This work presents a method named HISAT2 (hierarchical indexing for spliced alignment of transcripts 2) that can align both DNA and RNA sequences using a graph Ferragina Manzini index, and uses it to represent and search an expanded model of the human reference genome.
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Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown
TL;DR: This protocol describes all the steps necessary to process a large set of raw sequencing reads and create lists of gene transcripts, expression levels, and differentially expressed genes and transcripts.
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Sex chromosomes and the evolution of sexual dimorphism.
TL;DR: The idea that sex chromosomes also play an important role in the evolution of sexually dimorphic traits is evaluated and how the sex chromosomes can facilitate this evolution is suggested.