Journal ArticleDOI
Why does dosage compensation differ between XY and ZW taxa
TLDR
It is proposed that the extensive male bias on Z chromosomes is caused by the functional properties of male-adapted genes, which make them unsuitable for high expression in females, and that ZW females are dosage-compensated to a point where they have achieved enough compensation to maintain the integrity of critical networks.About:
This article is published in Trends in Genetics.The article was published on 2010-01-01. It has received 58 citations till now. The article focuses on the topics: Dosage compensation & X chromosome.read more
Citations
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Journal ArticleDOI
Are all sex chromosomes created equal
Doris Bachtrog,Mark Kirkpatrick,Judith E. Mank,Stuart F. McDaniel,J. Chris Pires,William R. Rice,Nicole Valenzuela +6 more
TL;DR: This work elucidate how the differences among these systems can be exploited to gain insights about general evolutionary processes, genome structure, and gene expression and suggest directions for research that will greatly increase general understanding of the forces driving sex-chromosome evolution in diverse organisms.
Journal ArticleDOI
Comparative sex chromosome genomics in snakes: differentiation, evolutionary strata, and lack of global dosage compensation.
TL;DR: Analysis of the genomes and transcriptomes of snake species with homomorphic and heteromorphic sex chromosomes reveals the evolutionary dynamics of sex chromosome differentiation.
Journal ArticleDOI
Restriction Site-Associated DNA Sequencing (RAD-seq) Reveals an Extraordinary Number of Transitions among Gecko Sex-Determining Systems
Tony Gamble,Tony Gamble,Jessi Coryell,Tariq Ezaz,Joshua Lynch,Daniel P. Scantlebury,David Zarkower +6 more
TL;DR: Support is found for the hypothesis that sex chromosome systems can readily become trap-like and it is found that adding even a small number of species from understudied clades can greatly enhance hypothesis testing in a model-based phylogenetic framework.
Journal ArticleDOI
How to make a sex chromosome.
TL;DR: This review considers each of these three questions in turn to address fundamental questions in the field, summarize the current understanding, and highlight important areas for future work.
Journal ArticleDOI
Sex chromosome dosage compensation: definitely not for everyone
TL;DR: The status of dosage compensation is surveyed to answer questions about what sorts of genes are likely to be dosage compensated, how dosage compensation evolves, and why complete dosage compensation appears to be limited to male heterogametic species.
References
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Journal ArticleDOI
Lethality and centrality in protein networks
TL;DR: It is demonstrated that the phenotypic consequence of a single gene deletion in the yeast Saccharomyces cerevisiae is affected to a large extent by the topological position of its protein product in the complex hierarchical web of molecular interactions.
Book
Sexual selection and the descent of man, 1871-1971
TL;DR: In the first full discussion of sexual selection since 1871, leading biologists brought modern genetic theory and behavior observation to bear on the subject as mentioned in this paper, and the result is a remarkably original and well-rounded view of the whole concept that will be invaluable especially to students of evolution and human sexual behavior.
Journal ArticleDOI
Intra-sexual selection in Drosophila.
TL;DR: Epigamic selection includes the major part of what Darwin meant by sexual selection, and is introduced to apply to characters which increased the fertility of a given mating and therefore had a selective value for the species as a whole.
Journal ArticleDOI
X-inactivation profile reveals extensive variability in X-linked gene expression in females
TL;DR: A comprehensive X-inactivation profile of the human X chromosome is presented, representing an estimated 95% of assayable genes in fibroblast-based test systems, and suggests a remarkable and previously unsuspected degree of expression heterogeneity among females.
Journal ArticleDOI
Evolutionary and biomedical insights from the rhesus macaque genome
Richard A. Gibbs,Jeffrey Rogers,Michael G. Katze,Roger E. Bumgarner,George M. Weinstock,Elaine R. Mardis,Karin A. Remington,Robert L. Strausberg,J. Craig Venter,Richard K. Wilson,Mark A. Batzer,Carlos Bustamante,Evan E. Eichler,Matthew W. Hahn,Ross C. Hardison,Kateryna D. Makova,Webb Miller,Aleksandar Milosavljevic,Robert E. Palermo,Adam Siepel,James M. Sikela,Tony Attaway,Stephanie Bell,Kelly E. Bernard,Christian J. Buhay,Mimi N. Chandrabose,Marvin Diep Dao,Clay Davis,Kimberly D. Delehaunty,Yan Ding,Huyen Dinh,Shannon Dugan-Rocha,Lucinda Fulton,Ramatu Ayiesha Gabisi,Toni T. Garner,Jennifer Godfrey,Alicia Hawes,Judith Hernandez,Sandra Hines,Michael Holder,Jennifer Hume,Shalini N. Jhangiani,Vandita Joshi,Ziad Khan,Ewen F. Kirkness,Andrew Cree,R. Gerald Fowler,Sandra L. Lee,Lora Lewis,Zhangwan Li,Yih-shin Liu,Stephanie M. Moore,Donna M. Muzny,Lynne V. Nazareth,Dinh Ngoc Ngo,Geoffrey Okwuonu,Grace Pai,David A. Parker,Heidie A. Paul,Cynthia Pfannkoch,Craig Pohl,Yu-Hui Rogers,San Juana Ruiz,Aniko Sabo,Jireh Santibanez,Brian W. Schneider,Scott M. Smith,Erica Sodergren,Amanda F. Svatek,Teresa Utterback,Selina Vattathil,Wesley C. Warren,Courtney Sherell White,Asif T. Chinwalla,Yucheng Feng,Aaron L. Halpern,LaDeana W. Hillier,Xiaoqiu Huang,Patrick Minx,Joanne O. Nelson,Kymberlie H. Pepin,Xiang Qin,Granger G. Sutton,Eli Venter,Brian P. Walenz,John W. Wallis,Kim C. Worley,Shiaw-Pyng Yang,Steven J. M. Jones,Marco A. Marra,Mariano Rocchi,Jacqueline E. Schein,Robert Baertsch,Laura Clarke,Miklós Csürös,Jarret Glasscock,R. Alan Harris,Paul Havlak,Andrew R. Jackson,Huaiyang Jiang,Yue Liu,David N. Messina,Yufeng Shen,Henry Xing-Zhi Song,Todd Wylie,Lan Zhang,Ewan Birney,Kyudong Han,Miriam K. Konkel,Jungnam Lee,Arian F.A. Smit,Brygg Ullmer,Hui Wang,Jinchuan Xing,Jinchuan Xing,Richard Burhans,Ze Cheng,John E. Karro,Jian Ma,Brian J. Raney,Xinwei She,Michael J. Cox,Jeffery P. Demuth,Laura J. Dumas,Sang-Gook Han,Janet A. Hopkins,Anis Karimpour-Fard,Young Ho Kim,Jonathan R. Pollack,Tomas Vinar,Charles Addo-Quaye,Jeremiah D. Degenhardt,Alexandra Denby,Melissa J. Hubisz,Amit Indap,Carolin Kosiol,Bruce T. Lahn,Heather A. Lawson,Alison Marklein,Rasmus Nielsen,Eric J. Vallender,Andrew G. Clark,Betsy Ferguson,Ryan D. Hernandez,Kashif Hirani,Hildegard Kehrer-Sawatzki,Jessica Kolb,Shobha Patil,Ling-Ling Pu,Yanru Ren,David Glenn Smith,David A. Wheeler,Ian Schenck,Edward V. Ball,Rui Chen,David Neil Cooper,Belinda Giardine,Fan Hsu,W. James Kent,Arthur M. Lesk,David L. Nelson,William E. O'Brien,Kay Prüfer,Peter D. Stenson,James C. Wallace,Hui Ke,Xiaoming Liu,Peng Wang,Andy Peng Xiang,Fan Yang,Galt P. Barber,David Haussler,David Haussler,Donna Karolchik,Andrew D. Kern,Robert M. Kuhn,Kayla E. Smith,Ann S. Zwieg +177 more
TL;DR: The genome sequence of an Indian-origin Macaca mulatta female is determined and compared with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families.