Vibrio Parahaemolyticus: A Review on Distribution, Pathogenesis, Virulence Determinants and Epidemiology.
TLDR
An updated review of the pathogenicity determinants and distribution of V. parahaemolyticus is provided to deliver a better understanding of the significance of this organism and its host–pathogen interactions.Abstract:
Vibrio parahaemolyticus is a Gram-negative, halophilic bacterium isolated from marine environments globally. After the consumption of contaminated seafood, V. parahaemolyticus causes acute gastroenteritis. To initiate infection, a wide range of virulence factors are required. A complex group of genes is known to participate in the pathogenicity of V. parahaemolyticus; however, to understand the full mechanism of infection, extensive research is yet required. V. parahaemolyticus has become the leading cause of seafood-related gastroenteritis in Japan, the United States and several other parts of the world. In addition, outbreaks caused by the pandemic clone of this organism are escalating and spreading universally. To minimize the risk of V. parahaemolyticus infection and warrant the safety of seafood, collaboration between governments and scientists is required. We herein provide an updated review of the pathogenicity determinants and distribution of V. parahaemolyticus to deliver a better understanding of the significance of V. parahaemolyticus and its host-pathogen interactions.read more
Citations
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Relationships between food and diseases: What to know to ensure food safety.
TL;DR: It is highlighted that to protect consumers from food-borne diseases, an integrated approach to food safety must be adopted which affects the entire food chain, from farm to fork.
Journal ArticleDOI
Prevalence and antibiotic resistance patterns of Vibrio parahaemolyticus isolated from different types of seafood in Selangor, Malaysia
Chia Wanq Tan,Yaya Rukayadi,Hanan Hasan,T. Y. Thung,Epeng Lee,Wendy Dayang Rollon,Hirofumi Hara,Ahmad Yaman Kayali,Mitsuaki Nishibuchi,Son Radu +9 more
TL;DR: The high prevalence of V. parahaemolyticus in seafood and multidrug-resistant isolates detected in this study could pose a potential risk to human health and hence appropriate control methods should be in place to minimize the potential contamination and prevent the emergence of antibiotic resistance.
Journal ArticleDOI
Antimicrobial and antivirulence efficacies of citral against foodborne pathogen Vibrio parahaemolyticus RIMD2210633
Juanjuan Cao,Huan Liu,Yi Wang,Xiaoxian He,Heyang Jiang,Jiaojiao Yao,Fei Xia,Yanni Zhao,Xuefeng Chen +8 more
TL;DR: It is demonstrated that citral may be of interest as alternative therapeutics against V. parahaemolyticus associated infections in seafood by exhibiting a reduced death rate and alleviating infection symptoms of the zebrafish model caused by V.Parahaemollyticus.
Journal ArticleDOI
A Novel Mouse Model of Enteric Vibrio parahaemolyticus Infection Reveals that the Type III Secretion System 2 Effector VopC Plays a Key Role in Tissue Invasion and Gastroenteritis.
Hyungjun Yang,Marcela de Souza Santos,Julia Lee,H. T. Law,Suneeta Chimalapati,Elena F. Verdu,Kim Orth,Bruce A. Vallance +7 more
TL;DR: An experimental model for this facultative intracellular pathogen is presented that enables further characterization of T3SS effectors as well as the corresponding host inflammatory response involved in the gastroenteritis caused by invasive V. parahaemolyticus.
Journal ArticleDOI
Isolation, detection of virulence genes, antibiotic resistance genes, plasmid profile, and molecular typing among Vibrio parahaemolyticus isolated in Malaysian seawater from recreational beaches and fish
Orooba Meteab Faja,Ali Abd Sharad,Khansa Mohammed Younis,Merriam Ghadhanfar Alwan,Basima Jasim Mohammed,Asmat Ahmad +5 more
TL;DR: This study demonstrated the occurrence of pathogenic, multi-antibiotic-resistant V. parahaemolyticus strains in Malaysian coastal waters and fish, and this could constitute potential public health risks.
References
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Emerging Infectious Diseases
TL;DR: Emerging infectious diseases, Emerging infectious diseases, کتابخانه دیجیتالی دانشگاه علوم پزش
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Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V cholerae
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TL;DR: This finding explains clinical features of V parahaemolyticus infections, which commonly include inflammatory diarrhoea and in some cases systemic manifestations such as septicaemia, distinct from those of V cholerae infections,Which are generally associated with non-inflammatory diarrhoeA.
Journal ArticleDOI
Global Dissemination of Vibrio parahaemolyticus Serotype O3:K6 and Its Serovariants
G. Balakrish Nair,Thandavarayan Ramamurthy,Sujit K. Bhattacharya,B. Dutta,Yoshifumi Takeda,David A. Sack +5 more
TL;DR: This review traces the genesis, virulence features, molecular characteristics, serotype variants, environmental occurrence, and global spread of this unique clone of V. parahaemolyticus that has now spread into Asia, America, Africa, and Europe.
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Pandemic Spread of an O3:K6 Clone of Vibrio parahaemolyticus and Emergence of Related Strains Evidenced by Arbitrarily Primed PCR and toxRS Sequence Analyses
Chiho Matsumoto,Jun Okuda,Masanori Ishibashi,Masaaki Iwanaga,Pallavi Garg,Thandavarayan Rammamurthy,Hin-Chung Wong,Angelo DePaola,Yung Bu Kim,M. John Albert,Mitsuaki Nishibuchi +10 more
TL;DR: This study presents strong evidence for the first pandemicity in the history of V. parahaemolyticus and reports a novel toxRS-targeted PCR method that will be useful in epidemiological investigation of the cases associated with the current pandemic spread.
Journal ArticleDOI
AMPylation of Rho GTPases by Vibrio VopS Disrupts Effector Binding and Downstream Signaling
TL;DR: It is found that VopS could act to covalently modify a conserved threonine residue on Rho, Rac, and Cdc42 with adenosine 5′-monophosphate (AMP), which prevented the interaction of Rho GTPases with downstream effectors, thereby inhibiting actin assembly in the infected cell.