Vogt-Koyanagi-Harada disease in a patient of chronic myeloid leukemia.
TLDR
This case report describes the concurrent development of Vogt–Koyanagi–Harada (VKH) disease in a 39 year old male patient of chronic myeloid leukemia (CML).Abstract:
This case report describes the concurrent development of Vogt–Koyanagi–Harada (VKH) disease in a 39 year old male patient of chronic myeloid leukemia (CML) The patient being reported was a known case of CML in remission with history of painless sudden loss of vision in both eyes Cases of leukemia can present with visual loss due to multiple ocular manifestations of leukemia itself or side effects of modern drugs used for its treatment Clinical examination and multimodal imaging of our patient were suggestive of concurrent development of VKH The patient was started on oral steroids, to which he showed a good response Thus, the cases of CML may rarely develop concurrent ocular disorders not related to leukemia These associated ocular disorders need to be distinguished from the ocular manifestations of leukemia itself Our case highlights the concurrent development of VKH as the etiology of visual loss in a case of CMLread more
Citations
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Vogt-Koyanagi-Harada disease like presentation in patients with chronic myeloid leukemia
TL;DR: CML patients can have features similar to VKH even during stable hematological phase and may be possibly associated with the use of tyrosine kinase inhibitors, hence it is important not to misdiagnose and treat such patients with long term immunomodulators.
Journal ArticleDOI
Ponatinib Inducing a Panuveitis with Choroidal Effusions and Neurosensory Retinal Detachment in a Patient with Chronic Myeloid Leukaemia.
TL;DR: In this paper, the case of a 50 year old male patient being treated for chronic myeloid leukemia by the tyrosine kinase inhibitor, Ponatinib, was presented.
Journal ArticleDOI
Acute lymphocytic leukemia with initial manifestation of serous retinal detachment and choroidal thickening: case report and literature review.
TL;DR: In this article, the authors describe a patient who had acute lymphocytic leukemia with exudative retinal detachment (RD), which mimicked Vogt-Koyanagi-Harada disease (VKH).
References
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Journal ArticleDOI
Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: report of an international committee on nomenclature.
Russell W. Read,Gary N. Holland,Narsing A. Rao,Khalid F. Tabbara,Shigeaki Ohno,Lourdes Arellanes-García,Paola Pivetti-Pezzi,Howard H. Tessler,Masahiko Usui +8 more
TL;DR: In this article, the authors present revised criteria for the diagnosis of Vogt-Koyanagi-Harada disease, a chronic, bilateral, granulomatous ocular and multisystem inflammatory condition of unknown cause.
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Phylogenetic Analysis of Rhinosporidium seeberi’s 18S Small-Subunit Ribosomal DNA Groups This Pathogen among Members of the Protoctistan Mesomycetozoa Clade
TL;DR: It is found that this enigmatic pathogen of humans and animals clusters with a novel group of fish parasites referred to as the DRIP clade, near the animal-fungal divergence, and is proposed to name this monophyletic clade Mesomycetozoa to reflect the group’s phylogenetic association within the Eucarya.
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Ocular side-effects associated with imatinib mesylate (Gleevec).
TL;DR: This retrospective case series describes ocular side-effects associated with imatinib mesylate (Gleevec) and the clinical characteristics of these adverse reactions, including periorbital edema and epiphora.
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Medical therapy of rhinosporidiosis with dapsone
TL;DR: Clinical, histopathological and ultrastructural studies in three cases of rhinosporidiosis show complete remission of infection within one year of therapy with dapsone.
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Acute Vogt-Koyanagi-Harada disease in enhanced spectral-domain optical coherence tomography.
TL;DR: The membranous structure that can be seen in eyes with acute VKH disease seems to represent a portion of the outer segment layer that has become separated from the inner segment layer by cystoid spaces.