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Journal ArticleDOI

X-ray diffraction computed tomography

G. Harding, +2 more
- 01 Jul 1987 - 
- Vol. 14, Iss: 4, pp 515-525
TLDR
The dose and sensitivity of x-ray diffraction CT are compared with those of conventional transmission CT, and possibilities for refinement of the technique by improving the momentum resolution are discussed.
Abstract
Coherent scattering of x-ray photons leads to the phenomenon of x-ray diffraction, which is widely used for determining atomic structure in materials science. A technique [x-ray diffraction computed tomography (CT)] is described, analogous to conventional CT, in which the x-ray diffraction properties of a stack of two-dimensional object sections may be imaged. The technique has been investigated using a first generation (single pencil beam) CT scanner to measure small angle coherent scatter, in addition to the customary transmitted radiation. Diffraction data from a standard CT performance phantom obtained with this new technique and with an x-ray diffractometer are compared. The agreement is satisfactory bearing in mind the poor momentum resolution of our apparatus. The dose and sensitivity of x-ray diffraction CT are compared with those of conventional transmission CT. Diffraction patterns of some biological tissues and plastics presented in a companion paper indicate the potential of x-ray diffraction CT for tissue discrimination and material characterization. Finally, possibilities for refinement of the technique by improving the momentum resolution are discussed.

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Journal ArticleDOI

Micro-computed tomography - Current status and developments

TL;DR: The recent rapid increase in interest in tomographic imaging of small animals and of human (and large animal) organ biopsies is driven largely by drug discovery, cancer detection/monitoring, phenotype identification and/or characterization, and development of disease detection methods and monitoring efficacies of drugs in disease treatment as mentioned in this paper.
Journal ArticleDOI

Medical applications of synchrotron radiation.

TL;DR: The medical imaging and therapeutic technologies that are based on the use of radiation are reviewed briefly, with special emphasis on the recent developments of synchrotron radiation (SR) methods.
Journal ArticleDOI

Probing the structure of heterogeneous diluted materials by diffraction tomography.

TL;DR: The potential of coupling pencil-beam tomography with X-ray diffraction to examine unidentified phases in nanomaterials and polycrystalline materials is shown, enabling a multimodal analysis of prime importance in materials science, chemistry, geology, environmental science, medical science, palaeontology and cultural heritage.
Journal ArticleDOI

X-ray scatter signatures for normal and neoplastic breast tissues

TL;DR: It has been found that tissue types can be characterized on the basis of the shape of the scatter spectrum and on its relative intensity, and suggests that if particular values of momentum transfer are monitored, a discriminating signal could be obtained.
Journal ArticleDOI

Molecular imaging in small animals--roles for micro-CT.

TL;DR: X‐ray micro‐CT is currently used primarily to generate 3D images of micro‐architecture and the regional distribution of administered radiopaque indicators, within intact rodent organs or biopsies from large animals and humans.
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