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RNA staining indicates that sponge bodies contain RNA.
Here we demonstrate that this RNA has the biological properties of a satellite RNA: it requires the presence of helper virus (BYDV genomic) RNA for replication and the helper RNA does not require the satellite.
Additionally, we demonstrate that labeling is specific to the ribozyme sequences, as FIA does not react nonspecifically with RNA.
Discoveries demonstrating that RNA can serve genetic, catalytic, structural, and regulatory roles have provided strong support for the existence of an RNA World that preceded the origin of life as we know it.
Open accessJournal ArticleDOI
P. Zhang, R. Rycyna, Peter B. Moore 
15 Citations
72, 3482-3484), which suggests that 5S RNA does not have a tightly folded, tRNA-like, tertiary structure.
The conserved GCVYAVEF octamer does not bind RNA directly as suggested earlier, but may assist with the proper folding of the central RNA-binding site.
Open accessJournal Article
10 Citations
Building on earlier hypotheses and hints of an ancient RNA world, more recent data have shown that the RNA world is alive and well, and had been either underappreciated or poorly described.
Taken together, we have concluded that LXRBSV acts as an RNA transcript not as a protein.
The widespread biological functions of RNA have made this molecule a reoccurring theme in basic and translational research, warranting it the transcendence from classically studied "cellular" RNA to "smart" RNA.
Moreover, we demonstrated that CS probably does not bind to RNA.