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These results show that very high concentrations of some commonly used essential oil constituents appear to have the potential to interact with estrogen receptors, although the biological significance of this is uncertain.
The marked increase in serum estrogen levels also suggests increased aromatization.
The effect was more pronounced at lower concentrations of estrogen, suggesting estrogen levels were the dominant factor.
Fresh soy oil offered protection in the estrogen-deficient state, as these rats had similar features to those of the NC group.
The present results confirm earlier findings and point toward a link between estrogen metabolism and estrogen antioxidant activity.
Journal ArticleDOI
R. X.-D. Song, Richard J. Santen 
01 Jan 2003-Apoptosis
109 Citations
The effects of estrogen are estrogen-receptor dependent.