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How does the expression of Pregnane X receptor (PXR) change during the progression of Alzheimer's disease? 

Nuclear receptor
Xenobiotic
Corepressor
Constitutive androstane receptor
Histone methyltransferase activity
Best insight from top research papers

The expression of PXR is not specifically mentioned in the abstracts provided in the context of Alzheimer's disease. Therefore, there is no information available on how the expression of PXR changes during the progression of Alzheimer's disease.

Answers from top 5 papers

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Papers (5)Insight
Open access•Journal Article•DOI
The role of pregnane X receptor (PXR) in substance metabolism
Ye Lv, Yi-Yang Luo, Huiwen Ren, Chengcheng Li, Zhi Xin-yue Xiang, Zhi-Lin Luan 
16 Aug 2022-Frontiers in Endocrinology
3 Citations
The provided paper does not mention anything about the expression of Pregnane X receptor (PXR) during the progression of Alzheimer's disease.
Journal Article•DOI
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism.
Tomas Smutny, Lucie Hyrsova, Albert Braeuning, Magnus Ingelman-Sundberg, Petr Pavek 
01 Jan 2021-Archives of Toxicology
9 Citations
The provided paper does not mention anything about the expression of Pregnane X receptor (PXR) during the progression of Alzheimer's disease.
Open access•Journal Article•DOI
Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions
Petr Pavek
25 Nov 2016-Frontiers in Pharmacology
107 Citations
The provided paper does not mention anything about the expression of Pregnane X receptor (PXR) during the progression of Alzheimer's disease.
Open access•Journal Article•DOI
Regulation of PXR Function by Coactivator and Corepressor Proteins: Ligand Binding Is Just the Beginning.
Juan Pablo Rigalli, Dirk Theile, Julie Nilles, Johanna Weiss 
12 Nov 2021-Cells
6 Citations
The provided paper does not mention anything about the expression of Pregnane X receptor (PXR) during the progression of Alzheimer's disease.
Journal Article•DOI
Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.
Ramanjulu Joshi M, Shawn P. Williams, Ami S. Lakdawala, Demartino Michael P, Yunfeng Lan, Robert W. Marquis 
10 Aug 2021-ACS Medicinal Chemistry Letters
1 Citations
The provided paper does not mention anything about the expression of Pregnane X receptor (PXR) during the progression of Alzheimer's disease.

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